Advances in PET Imaging of Large Vessel Vasculitis: An Update and Future Trends

IF 4.6 2区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Seminars in nuclear medicine Pub Date : 2024-03-27 DOI:10.1053/j.semnuclmed.2024.03.001

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Abstract

Systemic vasculitides are autoimmune diseases characterized by inflammation of blood vessels. They are categorized based on the size of the preferentially affected blood vessels: large-, medium-, and small-vessel vasculitides. The main forms of large-vessel vasculitis include giant cell arteritis (GCA) and Takayasu arteritis (TAK). Depending on the location of the affected vessels, various imaging modalities can be employed for diagnosis of large vessel vasculitis: ultrasonography (US), magnetic resonance angiography (MRA), computed tomography angiography (CTA), and [¹⁸F]-fluoro-2-deoxy-d-glucose positron emission tomography/computed tomography (FDG-PET/CT). These imaging tools offer complementary information about vascular changes occurring in vasculitis. Recent advances in PET imaging in large vessel vasculitis include the introduction of digital long axial field-of-view PET/CT, dedicated acquisition, quantitative methodologies, and the availability of novel radiopharmaceuticals. This review aims to provide an update on the current status of PET imaging in large vessel vasculitis and to share the latest developments on imaging vasculitides.

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大血管脉管炎 PET 成像的进展：最新进展与未来趋势

全身性血管炎是以血管发炎为特征的自身免疫性疾病。根据受影响血管的大小，可将其分为大、中、小血管炎。大血管炎主要包括巨细胞动脉炎（GCA）和高安动脉炎（TAK）。根据受影响血管的位置，大血管炎的诊断可采用多种成像模式：超声波成像（US）、磁共振血管成像（MRA）、计算机断层扫描血管成像（CTA）和[18F]-氟-2-脱氧-d-葡萄糖正电子发射断层扫描/计算机断层扫描（FDG-PET/CT）。这些成像工具提供了有关脉管炎血管变化的互补信息。大血管炎 PET 成像的最新进展包括引进了数字长轴视场 PET/CT、专用采集、定量方法和新型放射性药物。本综述旨在介绍大血管炎 PET 成像的最新现状，并分享血管炎成像的最新进展。

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来源期刊

Seminars in nuclear medicine 医学-核医学

CiteScore

9.80

自引率

6.10%

发文量

审稿时长

14 days

期刊介绍： Seminars in Nuclear Medicine is the leading review journal in nuclear medicine. Each issue brings you expert reviews and commentary on a single topic as selected by the Editors. The journal contains extensive coverage of the field of nuclear medicine, including PET, SPECT, and other molecular imaging studies, and related imaging studies. Full-color illustrations are used throughout to highlight important findings. Seminars is included in PubMed/Medline, Thomson/ISI, and other major scientific indexes.