Irritable bowel syndrome

Abstract

Irritable bowel syndrome (IBS) is a disorder of brain–gut interaction (formerly known as a functional gastrointestinal disorder) typically characterized by at least weekly abdominal pain associated with a change in frequency and form of the stool. IBS is common, with a population prevalence of around 5%. It is associated with a marked reduction in quality of life and significant healthcare expenditure. Its pathophysiology remains incompletely understood. IBS is subclassified according to the predominant bowel habit. Treatments are directed towards improving the predominant symptoms and include dietary/lifestyle modifications, medication and psychological interventions.