Effects of Endoscopic Sinus Surgery on Olfactory Bulb Volume among Patients with Chronic Rhinosinusitis: A Systematic Review and Meta-Analysis.

IF 2.5 3区医学 Q1 OTORHINOLARYNGOLOGY American Journal of Rhinology & Allergy Pub Date : 2024-07-01 Epub Date: 2024-03-28 DOI:10.1177/19458924241241874

Xincen Jiang, Tianhao Huang, Feifan Chang, Yu Song, Dawei Wu

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Abstract

Background: Endoscopic sinus surgery (ESS) could significantly improve olfactory function among patients with chronic rhinosinusitis (CRS). This study aimed to perform a meta-analysis to evaluate the effect of ESS on the olfactory bulb volume (OBV) among patients with CRS.

Methods: A systemic search of PubMed, Medline, Embase, Web of Science, and other databases was conducted to identify studies assessing OBV changes in patients with CRS after ESS utilizing magnetic resonance imaging.

Results: A total of four studies with 168 participants were included. Comparing the changes in OBV of patients with CRS before and after surgery within 3-6 months, the ESS significantly improved the overall OBV (P = 0.005, I²= 66%), with the left OBV increased by 5.57mm³ (P = 0.84, I²= 0%), and the right OBV increased by 8.63mm³ (P = 0.09, I²= 53%). A difference in OBV persists between healthy controls and patients with CRS 3-6 months after ESS. The overall OBV of patients with CRS after ESS was significantly smaller than controls (mean difference = -3.84, P = 0.04), with a mean difference of 4.13mm³ on the left side (P = 0.72, I²= 0%), and a mean difference of 3.22mm³ on the right side (P = 0.0001, I²= 89%).

Conclusions: ESS significantly increases the OBV among patients with CRS.

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内窥镜鼻窦手术对慢性鼻窦炎患者嗅球体积的影响：系统回顾与元分析》。

背景：内窥镜鼻窦手术（ESS）可显著改善慢性鼻窦炎（CRS）患者的嗅觉功能。本研究旨在进行一项荟萃分析，评估ESS对CRS患者嗅球体积（OBV）的影响：方法：对PubMed、Medline、Embase、Web of Science和其他数据库进行了系统检索，以确定利用磁共振成像评估ESS后CRS患者嗅球体积变化的研究：结果：共纳入了四项研究，168 名参与者。比较CRS患者手术前后3-6个月内的OBV变化，ESS显著改善了整体OBV（P = 0.005，I2 = 66%），左侧OBV增加了5.57mm3（P = 0.84，I2 = 0%），右侧OBV增加了8.63mm3（P = 0.09，I2 = 53%）。健康对照组和 CRS 患者在 ESS 3-6 个月后的 OBV 仍存在差异。ESS后CRS患者的总体OBV明显小于对照组（平均差异=-3.84，P=0.04），左侧平均差异为4.13mm3（P=0.72，I2=0%），右侧平均差异为3.22mm3（P=0.0001，I2=89%）：结论：ESS可明显增加CRS患者的OBV。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

American Journal of Rhinology & Allergy 医学-耳鼻喉科学

CiteScore

5.60

自引率

11.50%

发文量

审稿时长

4-8 weeks

期刊介绍： The American Journal of Rhinology & Allergy is a peer-reviewed, scientific publication committed to expanding knowledge and publishing the best clinical and basic research within the fields of Rhinology & Allergy. Its focus is to publish information which contributes to improved quality of care for patients with nasal and sinus disorders. Its primary readership consists of otolaryngologists, allergists, and plastic surgeons. Published material includes peer-reviewed original research, clinical trials, and review articles.