Evaluating the contribution of the Glittre-ADL test in adults with cystic fibrosis.

IF 1.5 Q3 REHABILITATION Physiotherapy Research International Pub Date : 2024-04-01 DOI:10.1002/pri.2087

Vera Lucia Barros Abelenda, Cláudia Henrique da Costa, Mônica de Cássia Firmida, Agnaldo José Lopes

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Abstract

Background and objectives: Cardiopulmonary and skeletal muscle impairment and poor physical activity are potential contributors to reduced functional capacity in cystic fibrosis (CF). The Glittre-ADL test (TGlittre) has great potential for clinical use in adult CF adults, as it meets the need for a comprehensive assessment of physical function using tasks similar to activities of daily living. This study aimed to evaluate the performance of TGlittre in CF adults compared to the 6-min walk test (6MWT) and, secondarily, to quantify the associations of their results with pulmonary function, muscle strength, and health-related quality of life (HRQoL).

Methods: This cross-sectional study evaluated 34 CF adults and compared them with 34 subjects from a control group. The participants underwent the following assessments: functional capacity using TGlittre and 6MWT; spirometry; respiratory muscle strength; handgrip strength (HGS); and HRQoL using the Cystic Fibrosis Questionnaire-Revised (CFQ-R).

Results: While CF patients showed a longer time to perform TGlittre compared to controls (134 (119-150) versus 107 (95-126) % of the predicted time p = 0.0002), no difference between these groups was observed in the 6MWT. When the second TGlittre was compared to the first TGlittre, there was a significant decrease in total time for both CF patients (p < 0.0001) and controls (p = 0.0001). TGlittre time correlated with 6MWT distance (6MWD) (r_s = -0.641, p < 0.0001), HGS (r_s = -0.364, p = 0.034), peripheral oxygen saturation at the end of the test (r_s = -0.463, p = 0.006) and the "digestive symptoms" domain of CFQ-R (r_s = 0.376, p = 0.028). TGlittre time was shorter in patients who engaged in regular physical activity (3.10 (2.49-3.39) min versus 3.28 (2.95-3.53) min, p = 0.016).

Conclusions: TGlittre is more effective than the 6MWT in detecting limitations during exercise. There is an important learning effect of TGlittre in adult CF patients. TGlittre time was correlated with 6MWD, HGS, oxygen saturation level, and the patient's level of physical activity.

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评估 Glittre-ADL 测试对成年囊性纤维化患者的贡献。

背景和目的：心肺功能和骨骼肌损伤以及体力活动差是导致囊性纤维化（CF）患者功能减退的潜在因素。Glittre-ADL测试（TGlittre）具有很大的临床应用潜力，因为它满足了利用类似于日常生活活动的任务对身体功能进行全面评估的需求。本研究旨在评估 TGlittre 与 6 分钟步行测试（6MWT）相比在 CF 成人中的表现，其次量化它们的结果与肺功能、肌肉力量和健康相关生活质量（HRQoL）之间的关联：这项横断面研究对 34 名 CF 成人进行了评估，并将他们与对照组的 34 名受试者进行了比较。参与者接受了以下评估：使用 TGlittre 和 6MWT 进行的功能能力评估；肺活量测定；呼吸肌力量；手握力（HGS）；以及使用囊性纤维化问卷-修订版（CFQ-R）进行的 HRQoL：与对照组相比，CF 患者进行 TGlittre 的时间更长（134（119-150）% 预测时间对 107（95-126）% 预测时间，P = 0.0002），但在 6MWT 中未观察到两组间的差异。当第二次 TGlittre 与第一次 TGlittre 相比时，CF 患者的总时间（p s = -0.641，p s = -0.364，p = 0.034）、测试结束时的外周血氧饱和度（rs = -0.463，p = 0.006）和 CFQ-R 的 "消化症状 "域（rs = 0.376，p = 0.028）均显著减少。经常参加体育锻炼的患者的 TGlittre 时间更短（3.10 (2.49-3.39) 分钟对 3.28 (2.95-3.53) 分钟，p = 0.016）：结论：TGlittre 比 6MWT 更能有效检测运动过程中的限制。TGlittre对成年CF患者有重要的学习作用。TGlittre时间与6MWD、HGS、血氧饱和度和患者的运动水平相关。

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来源期刊

Physiotherapy Research International REHABILITATION-

CiteScore

3.30

自引率

5.90%

发文量

期刊介绍： Physiotherapy Research International is an international peer reviewed journal dedicated to the exchange of knowledge that is directly relevant to specialist areas of physiotherapy theory, practice, and research. Our aim is to promote a high level of scholarship and build on the current evidence base to inform the advancement of the physiotherapy profession. We publish original research on a wide range of topics e.g. Primary research testing new physiotherapy treatments; methodological research; measurement and outcome research and qualitative research of interest to researchers, clinicians and educators. Further, we aim to publish high quality papers that represent the range of cultures and settings where physiotherapy services are delivered. We attract a wide readership from physiotherapists and others working in diverse clinical and academic settings. We aim to promote an international debate amongst the profession about current best evidence based practice. Papers are directed primarily towards the physiotherapy profession, but can be relevant to a wide range of professional groups. The growth of interdisciplinary research is also key to our aims and scope, and we encourage relevant submissions from other professional groups. The journal actively encourages submissions which utilise a breadth of different methodologies and research designs to facilitate addressing key questions related to the physiotherapy practice. PRI seeks to encourage good quality topical debates on a range of relevant issues and promote critical reflection on decision making and implementation of physiotherapy interventions.