Development of a rapid tool for screening financial toxicity based on the comprehensive score for financial toxicity

IF 2 Q3 HEALTH POLICY & SERVICES Journal of Cancer Policy Pub Date : 2024-03-27 DOI:10.1016/j.jcpo.2024.100475
Ling-ling Wang , Richard Huan Xu
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Abstract

Objective

This study aimed to use item response theory (IRT) to develop and validate a short version of the Chinese COmprehensive Score for financial Toxicity (COST-S-C) in patients with cancer.

Methods

A total of 500 patients with cancer participated in the survey. Confirmatory factor analysis (CFA) was used to assess the factor structure of the COST-S-C. A two-parameter IRT model was used to examine the item fit of the COST-S-C. Item discrimination, item characteristic curves (ICCs), item information curves (IICs), and item fit were estimated. Differential item functioning (DIF) was assessed for participants’ gender and age. Reliability, convergent and discriminant validity was examined as well as estimating the optimal cut-off points of the COST-S-C.

Results

The CFA results supported the bi-factor structure of the COST-S-C. The IRT analysis findings revealed that several items showed problems with the ICCs, providing little information in terms of IICs as well as poor discrimination. Item 5 showed a negligible DIF problem with age. A valid 3-item COST-S-C scale and its optimal cut-off point was developed.

Conclusions

The COST-S-C is a valid and quick screening tool used to distinguish patients with cancer who report significant financial toxicity in various medical settings.

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基于金融毒性综合评分,开发筛选金融毒性的快速工具
方法 共有500名癌症患者参加了调查。采用确证因子分析(CFA)评估COST-S-C的因子结构。采用双参数 IRT 模型检验 COST-S-C 的项目拟合度。对项目区分度、项目特征曲线(ICC)、项目信息曲线(IIC)和项目拟合度进行了估计。根据参与者的性别和年龄评估了项目功能差异(DIF)。结果CFA结果支持COST-S-C的双因素结构。IRT分析结果显示,有几个项目的ICCs出现了问题,提供的IICs信息很少,区分度也很低。项目 5 显示出与年龄有关的 DIF 问题,可以忽略不计。结论COST-S-C是一种有效、快速的筛查工具,用于区分在各种医疗环境中报告有明显经济毒性的癌症患者。
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来源期刊
Journal of Cancer Policy
Journal of Cancer Policy Medicine-Health Policy
CiteScore
2.40
自引率
7.70%
发文量
47
审稿时长
65 days
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