The impact of water pollution on the health of older people

IF 3.9 2区 医学 Q2 GERIATRICS & GERONTOLOGY Maturitas Pub Date : 2024-03-30 DOI:10.1016/j.maturitas.2024.107981
Stefania Bochynska , Anna Duszewska , Marzena Maciejewska-Jeske , Marcin Wrona , Anna Szeliga , Michal Budzik , Aleksandra Szczesnowicz , Gregory Bala , Mateusz Trzcinski , Blazej Meczekalski , Roman Smolarczyk
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Abstract

Water pollution exerts a negative impact on the health of both women and men, inducing hormonal changes, accelerating aging, and consequently leading to the premature onset of age-related health problems. Water pollutants can in general be classified as chemical (both organic and inorganic), physical, and biological agents. Certain chemical pollutants have been found to disrupt hormonal balance by blocking, mimicking, or disrupting functions within the intricate homeostasis of the human body.

Moreover, certain water pollutants, including specific pesticides and industrial chemicals, have been associated with neurological and psychiatric disorders, such as mood swings, depression, cognitive decline, and anxiety, impacting both women and men. Water pollution is also associated with physical ailments, such as diarrhea, skin diseases, malnutrition, and cancer. Exposure to specific pollutants may promote premature menopause and vasomotor symptoms, elevate the risk of cardiovascular disease, and reduce bone density. In men, exposure to water pollution has been shown to reduce LH, FSH, and testosterone serum levels. The oxidative stress induced by pollutants prompts apoptosis of Sertoli and germ cells, inhibiting spermatogenesis and altering the normal morphology and concentration of sperm. Environmental estrogens further contribute to reduced sperm counts, reproductive system disruptions, and the feminization of male traits.

Studies affirm that men generally exhibit a lower susceptibility than women to hormonal changes and health issues attributed to water pollutants. This discrepancy may be attributed to the varied water-related activities which have traditionally been undertaken by women, as well as differences in immune responses between genders. The implementation of effective measures to control water pollution and interventions aimed at safeguarding and enhancing the well-being of the aging population is imperative.

The improvement of drinking water quality has emerged as a potential public health effort with the capacity to curtail the onset of cognitive impairment and dementia in an aging population.

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水污染对老年人健康的影响
水污染对女性和男性的健康都有负面影响,会诱发荷尔蒙变化,加速衰老,从而导致与年龄相关的健康问题过早出现。水污染物一般可分为化学(有机和无机)、物理和生物制剂。此外,某些水污染物,包括特定的杀虫剂和工业化学品,与神经和精神疾病有关,如情绪波动、抑郁、认知能力下降和焦虑,对女性和男性都有影响。水污染还与身体疾病有关,如腹泻、皮肤病、营养不良和癌症。接触特定的污染物可能会导致更年期提前和血管运动症状,增加心血管疾病的风险,并降低骨密度。在男性中,接触水污染已被证明会降低 LH、FSH 和睾丸激素的血清水平。污染物诱发的氧化应激促使 Sertoli 细胞和生殖细胞凋亡,抑制精子生成,改变精子的正常形态和浓度。环境雌激素进一步导致精子数量减少、生殖系统紊乱和男性特征女性化。研究证实,男性通常比女性更容易受到水污染物导致的荷尔蒙变化和健康问题的影响。这种差异可能是由于传统上由女性承担的各种与水有关的活动,以及两性之间免疫反应的差异造成的。当务之急是采取有效措施控制水污染,并采取干预措施保障和提高老龄人口的福祉。改善饮用水质量已成为一项潜在的公共卫生工作,有能力遏制老龄人口认知障碍和痴呆症的发生。
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来源期刊
Maturitas
Maturitas 医学-妇产科学
CiteScore
9.10
自引率
2.00%
发文量
142
审稿时长
40 days
期刊介绍: Maturitas is an international multidisciplinary peer reviewed scientific journal of midlife health and beyond publishing original research, reviews, consensus statements and guidelines, and mini-reviews. The journal provides a forum for all aspects of postreproductive health in both genders ranging from basic science to health and social care. Topic areas include:• Aging• Alternative and Complementary medicines• Arthritis and Bone Health• Cancer• Cardiovascular Health• Cognitive and Physical Functioning• Epidemiology, health and social care• Gynecology/ Reproductive Endocrinology• Nutrition/ Obesity Diabetes/ Metabolic Syndrome• Menopause, Ovarian Aging• Mental Health• Pharmacology• Sexuality• Quality of Life
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