Efficacy of radiofrequency ablation vs. transcatheter arterial embolization for hepatic hemangiomas.

IF 2.3 4区 医学 Q3 GASTROENTEROLOGY & HEPATOLOGY European Journal of Gastroenterology & Hepatology Pub Date : 2024-06-01 Epub Date: 2024-03-28 DOI:10.1097/MEG.0000000000002724
Jushang Li, Shuaiguo Zhang, Chunmin Ning, Guoming Li, Shigang Guo
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Abstract

Objective: The objective of this study was to evaluate the safety and effectiveness of radiofrequency ablation (RFA) and transcatheter arterial chemoembolization (TACE) in the treatment of large hepatic hemangiomas (LHH) (5-9.9 cm in diameter).

Methods and materials: This study retrospectively collected data from 82 patients with LHH treated at Chaoyang Central Hospital. The study analyzed the differences in postoperative efficacy, operative time, blood routine, liver and kidney function on the first day after surgery, postoperative hospitalization time and postoperative complications.

Results: There were statistically significant differences in indicators such as white blood cell count, alanine aminotransferase, aspartate aminotransferase and total bilirubin on the first day after surgery between the RFA group (39 cases) and the TACE group (43 cases) ( P  < 0.001). Compared to RFA, LHH patients treated with TACE had a general complication rate of 39.5% (vs. 43.6%; P  = 0.7), a procedure-related complication rate of 30.2% (vs. 59.0%; P  = 0.009), an effective rate at 6-12 months postoperatively of 55.8% (vs. 82.1%; P  = 0.01), an operating-time of 41.2 ± 14.9 min (vs. 100.8 ± 35.5 min; P  < 0.001) and hospitalization costs of 17052.7 ± 1364.8 yuan (vs. 30952.1 ± 4327.6 yuan; P  < 0.001).

Conclusion: This study indicates that the efficacy of RFA in treating LHH is significantly superior to TACE. Microwave ablation and RFA appear to be safe treatments for LHH. The TACE group exhibited shorter operating-time, lower hospitalization costs and lower demands on cardiopulmonary function.

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射频消融与经导管动脉栓塞治疗肝血管瘤的疗效对比。
研究目的本研究旨在评估射频消融术(RFA)和经导管动脉化疗栓塞术(TACE)治疗大肝脏血管瘤(LHH)(直径5-9.9厘米)的安全性和有效性:本研究回顾性收集了82例在朝阳医院接受治疗的LHH患者的数据。研究分析了术后疗效、手术时间、血常规、术后第一天肝肾功能、术后住院时间和术后并发症的差异:结果:RFA组(39例)与TACE组(43例)术后第一天的白细胞计数、丙氨酸氨基转移酶、天门冬氨酸氨基转移酶、总胆红素等指标差异有统计学意义(P 结论:RFA组与TACE组术后第一天的白细胞计数、丙氨酸氨基转移酶、天门冬氨酸氨基转移酶、总胆红素等指标差异有统计学意义(P):本研究表明,RFA 治疗 LHH 的疗效明显优于 TACE。微波消融和射频消融似乎是治疗 LHH 的安全疗法。TACE 组的手术时间更短、住院费用更低,对心肺功能的要求也更低。
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来源期刊
CiteScore
4.40
自引率
4.80%
发文量
269
审稿时长
1 months
期刊介绍: European Journal of Gastroenterology & Hepatology publishes papers reporting original clinical and scientific research which are of a high standard and which contribute to the advancement of knowledge in the field of gastroenterology and hepatology. The journal publishes three types of manuscript: in-depth reviews (by invitation only), full papers and case reports. Manuscripts submitted to the journal will be accepted on the understanding that the author has not previously submitted the paper to another journal or had the material published elsewhere. Authors are asked to disclose any affiliations, including financial, consultant, or institutional associations, that might lead to bias or a conflict of interest.
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