Necrotizing mesenteric vasculitis in systemic lupus erythematosus.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-01-01 DOI:10.63032/XVZP4159
Maria Helena Lourenço, Ana Bento Silva, Jessica Sousa, Helena Oliveira, Inês Silva, Manuela Costa, Jaime Cunha Branco, Maria João Gonçalves
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Abstract

Systemic lupus erythematosus (SLE) is a multisystemic autoimmune disorder which may affect the gastrointestinal system. Half of the patients with SLE experience gastrointestinal symptoms, with the most common being nausea, vomiting, anorexia, and abdominal pain. Mesenteric vasculitis is a severe and rare complication of SLE and one of the most frequent causes of severe acute abdominal pain. The authors present a case of a 57-year-old woman with SLE who was diagnosed with necrotizing mesenteric vasculitis following a urinary septic shock. The patient was treated with high-dose corticosteroid therapy and cyclophosphamide, with resolution of the clinical picture.

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系统性红斑狼疮的坏死性肠系膜血管炎。
系统性红斑狼疮(SLE)是一种多系统自身免疫性疾病,可能会影响胃肠道系统。半数系统性红斑狼疮患者会出现胃肠道症状,其中最常见的是恶心、呕吐、厌食和腹痛。肠系膜血管炎是系统性红斑狼疮的一种严重而罕见的并发症,也是导致严重急性腹痛的最常见原因之一。作者介绍了一例患有系统性红斑狼疮的 57 岁女性患者,她在泌尿系统脓毒性休克后被诊断为坏死性肠系膜血管炎。患者接受大剂量皮质类固醇治疗和环磷酰胺治疗后,临床症状得到缓解。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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