Necrotizing mesenteric vasculitis in systemic lupus erythematosus.

IF 1.4 4区 医学 Q3 RHEUMATOLOGY ARP Rheumatology Pub Date : 2024-01-01 DOI:10.63032/XVZP4159
Maria Helena Lourenço, Ana Bento Silva, Jessica Sousa, Helena Oliveira, Inês Silva, Manuela Costa, Jaime Cunha Branco, Maria João Gonçalves
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Abstract

Systemic lupus erythematosus (SLE) is a multisystemic autoimmune disorder which may affect the gastrointestinal system. Half of the patients with SLE experience gastrointestinal symptoms, with the most common being nausea, vomiting, anorexia, and abdominal pain. Mesenteric vasculitis is a severe and rare complication of SLE and one of the most frequent causes of severe acute abdominal pain. The authors present a case of a 57-year-old woman with SLE who was diagnosed with necrotizing mesenteric vasculitis following a urinary septic shock. The patient was treated with high-dose corticosteroid therapy and cyclophosphamide, with resolution of the clinical picture.

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系统性红斑狼疮的坏死性肠系膜血管炎。
系统性红斑狼疮(SLE)是一种多系统自身免疫性疾病,可能会影响胃肠道系统。半数系统性红斑狼疮患者会出现胃肠道症状,其中最常见的是恶心、呕吐、厌食和腹痛。肠系膜血管炎是系统性红斑狼疮的一种严重而罕见的并发症,也是导致严重急性腹痛的最常见原因之一。作者介绍了一例患有系统性红斑狼疮的 57 岁女性患者,她在泌尿系统脓毒性休克后被诊断为坏死性肠系膜血管炎。患者接受大剂量皮质类固醇治疗和环磷酰胺治疗后,临床症状得到缓解。
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