Peripheral nerve stimulation (PNS): A valid and definitive therapeutical option for a case of anterior cutaneous nerve entrapment syndrome (ACNES).

Ezio Amorizzo, Francesca De Sanctis, Gianni Colini Baldeschi, Fernando Ricci, Giustino Varrassi
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Abstract

Anterior cutaneous nerve entrapment syndrome (ACNES) is a cause of moderate to severe chronic pain, hyperesthesia/hypoesthesia, and altered perception of heat/cold in a specific region of the anterior abdominal wall, referable to the territory of innervation of one or more anterior branches of the intercostal nerves. None of the therapeutic options currently available has proved to be effective in the long term or decisive. In recent years, we have begun to treat purely sensory neuropathies, such as this, with the implantation of wireless peripheral nerve stimulators (PNS), achieving the safety of modular and personalized analgesia. We report the case of a 41-year-old man suffering from ACNES of the 8th intercostal nerve for two years. We first performed two consecutive ultrasound-guided diagnostic blocks of the anterior cutaneous branch of the 8th intercostal right nerve and then elected the patient for ultrasound-guided nerve decompression followed by neuromodulation and pulsed-radiofrequency (PRF). Taking into account full employment, young age, and the likelihood of having to repeat the treatment several times, we considered him for Peripheral Nerve Stimulation (PNS) implantation under ultrasound guidance, and we implanted the wireless lead at the anterior branch of the right 8th intercostal nerve, and programmed tonic stimulation 100 Hz PW 200 ms. The patient reported immediate pain relief and never took medication for this problem again, at two years follow-up. PNS has had an increasing role in the management of chronic neuropathic pain, especially in merely sensitive neuropathies like ACNES. We support future research on this theme.

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周围神经刺激(PNS):针对前皮神经卡压综合征(ACNES)病例的有效而明确的治疗方案。
前皮神经卡压综合征(ACNES)是导致腹壁前部特定区域出现中度至重度慢性疼痛、感觉过敏/麻木过度以及冷热感知改变的原因之一,该区域位于肋间神经的一个或多个前支的支配区域。目前可供选择的治疗方法中,没有一种被证明是长期有效或决定性的。近年来,我们开始通过植入无线外周神经刺激器(PNS)来治疗类似的纯感觉神经病,实现了模块化和个性化镇痛的安全性。我们报告了一名 41 岁男性的病例,他患有第 8 肋间神经 ACNES 已达两年之久。我们首先在超声引导下对右侧第 8 肋间神经前皮支进行了连续两次诊断性阻滞,然后为患者选择了超声引导下神经减压术,随后进行了神经调控和脉冲射频(PRF)治疗。考虑到患者充分就业、年龄较小且可能需要多次重复治疗,我们考虑在超声引导下为其植入外周神经刺激器(PNS),并在右侧第 8 肋间神经前支植入无线导线,设定强直性刺激 100 Hz PW 200 ms。患者表示疼痛立即得到缓解,并且在两年的随访中再也没有因为这个问题服药。PNS 在慢性神经病理性疼痛的治疗中发挥着越来越重要的作用,尤其是在 ACNES 等单纯敏感性神经病中。我们支持今后就这一主题开展研究。
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