Evaluation of Anti-Rheumatoid Arthritis potential Activity of Persimmon juice in female rats induced by Complete Freund's Adjuvant

S. Negm, Hany gaber elmasry, Alaa Aboraya
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Abstract

: This study aimed to evaluate the potential activity of persimmon fruit juice (PFJ) against rheumatoid arthritis (RA). The study conducted on 35 female albino (Sprague-Dawley) rats weighing (170±10g)were randomly divided into five groups(7each) fed on basal diet the first group was the control negative and four other groups were injured with 1ml/kg of Freund's complete adjuvant into the left hind knee joint for7days to induce RA. They were re-divided as follows: group2 served as the control positive group and the three other groups were treated with different doses of PFJ (low)1ml, (high)2ml/kg bw and drugs
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评估柿子汁在完全弗氏佐剂诱导的雌性大鼠中抗类风湿关节炎的潜在活性
:本研究旨在评估柿果汁(PFJ)对类风湿性关节炎(RA)的潜在活性。研究以 35 只体重为(170±10 克)的雌性白化(Sprague-Dawley)大鼠为对象,随机分为 5 组(每组 7 只),以基础饮食喂养,第一组为对照阴性组,其他 4 组用 1 毫升/千克的弗氏完全佐剂损伤左后膝关节,诱发 RA,持续 7 天。它们被重新分为以下几组:第 2 组为对照阳性组,其他三组分别用不同剂量的 PFJ(低)1 毫升、(高)2 毫升/千克体重和药物进行治疗;第 3 组为对照阴性组,其他三组分别用不同剂量的 PFJ(低)1 毫升、(高)2 毫升/千克体重和药物进行治疗。
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