Benign Prostatic Hyperplasia and the Risk of Falls in Older Men: Insights From a Population-Based Study on Geriatric Morbid Conditions

IF 17.7 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-03-01 DOI:10.5213/inj.2448064.032
Sung Jin Kim, Donghyun Lee, S. Park, S. Pak, Young Goo Lee, Sung-Tae Cho
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Abstract

Purpose The purpose of this study was to explore the association between benign prostatic hyperplasia (BPH) and the incidence of falls from the perspective of geriatric morbid conditions. Methods Data were sourced from the triennial National Survey of Older Koreans conducted by the Ministry of Health and Welfare (2017–2020). In total, 8,135 male participants aged 65 and older were included, and information was gathered through questionnaires and physical measurements. Logistic regression analysis was utilized to determine the impact of BPH on the risk of falls, and subgroup analyses were conducted to examine the influence of BPH on specific types of falls. Results Of the participants, 15.2% (1,238 of 8,135) reported that their BPH treatment exceeded 3 months, and 8.0% (648 of 8,135) reported experiencing falls, with 61.4% (398/648) of these falls resulting in injuries. A significant association was identified between BPH and both falls (odds ratio [OR], 1.798; 95% confidence interval [CI], 1.479–2.185) and falls with injuries (OR, 2.133; 95% CI, 1.689–2.694). A subgroup analysis indicated a correlation between BPH and falls in groups having one (OR, 1.912; 95% CI, 1.356–2.694) and 2 or more conditions (OR, 1.856; 95% CI, 1.455–2.367) involving visual and auditory impairments, cognitive decline, depression, lower motor weakness, and limitations in daily activities. Conclusions The findings indicate that BPH contributes to the incidence of falls among older men, particularly those with comorbid conditions. Considering the heightened fall risk among elderly individuals suffering from multiple morbidities, particularly those with BPH, targeted interventions are essential for mitigating the risk of falls in this vulnerable group.
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良性前列腺增生与老年男性跌倒的风险:基于人群的老年病学研究的启示
目的 本研究旨在从老年病的角度探讨良性前列腺增生症(BPH)与跌倒发生率之间的关系。方法 数据来源于韩国保健福祉部开展的三年一次的韩国老年人全国调查(2017-2020 年)。共纳入 8135 名 65 岁及以上男性参与者,通过问卷调查和身体测量收集信息。利用逻辑回归分析确定良性前列腺增生症对跌倒风险的影响,并进行亚组分析研究良性前列腺增生症对特定类型跌倒的影响。结果 在参与者中,15.2%(8135 人中的 1238 人)称其良性前列腺增生症的治疗时间超过 3 个月;8.0%(8135 人中的 648 人)称曾有过跌倒经历,其中 61.4%(398/648)的跌倒导致了受伤。研究发现,良性前列腺增生症与跌倒(几率比 [OR],1.798;95% 置信区间 [CI],1.479-2.185)和跌倒受伤(OR,2.133;95% 置信区间 [CI],1.689-2.694)之间存在明显关联。一项亚组分析表明,在患有一种(OR,1.912;95% CI,1.356-2.694)和两种或两种以上(OR,1.856;95% CI,1.455-2.367)疾病的人群中,良性前列腺增生症与跌倒之间存在相关性,这些疾病涉及视觉和听觉障碍、认知能力下降、抑郁、下肢运动无力以及日常活动受限。结论 研究结果表明,良性前列腺增生症是导致老年男性跌倒的原因之一,尤其是那些患有合并症的老年男性。考虑到患有多种疾病的老年人,尤其是患有良性前列腺增生症的老年人跌倒风险较高,有针对性的干预措施对于降低这一弱势群体的跌倒风险至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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