Some aspects of laboratory diagnostics of ophthalmodemodecosis

D. A. Popova, Y. V. Kursakova
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Abstract

Demodicosis occupies a leading position among all dermatoses. According to ICD-10, it is not distinguished as a separate disease; it belongs to the class of parasitic diseases. The relevance of studying the problem of ophthalmodemodecosis is caused by its high prevalence and contagiousness, chronic course, an open issue of the role of the Demodex mite in the occurrence of inflammatory eye diseases, as well as the lack of effective methods for treating and preventing this pathology. In addition, Demodex causes discomfort and contributes to the occurrence of cosmetic defects, which in turn worsens the patient’s quality of life.The aim. To present a review of the literature data and our own results of laboratory diagnostics of ophthalmodemodecosis.Materials and methods. The article presents clinical cases of demodectic eyelid lesions with different disease outcomes in case of similar treatment. Laboratory diagnostics included drawing up an acarogram. Epilated eyelashes were used as a material for detecting mites on eyelids. Counting of individuals was carried out using light microscopy; all forms of mite development were taken into account. The work presents the statistics on the frequency of examination of patients with suspected demodicosis at different times of the year, confirming the seasonality of this disease. The literature review included data on the history of studying the Demodex mite, existing hypotheses and theories about its pathogenesis, as well as the information on domestic and foreign methods of treating ophthalmodecosis, including modern hardware techniques.Results. Demodex mites play a significant role in the development of blepharitis and blepharoconjunctivitis. It is important to consider that demodicosis can occur against the background of inflammatory eye diseases of another etiology. Therapy for  ophthalmodemodecosis currently remains complex, lengthy and  ineffective. When assessing the results of an acarogram, any detected stages of a mite are clinically significant, and there isn’t a direct relationship between the number of detected mites and the severity of clinical manifestations in all cases.
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眼病实验室诊断的几个方面
脱皮症在所有皮肤病中占主要地位。根据《国际疾病分类》(ICD-10),它不作为一种单独的疾病,而是属于寄生虫病。研究眼部蜕皮病问题的意义在于它的高发病率和传染性、慢性过程、蜕皮螨在炎症性眼病发生中的作用这一未决问题,以及缺乏治疗和预防这种病症的有效方法。此外,螨虫还会引起不适,导致外观缺陷的发生,进而恶化患者的生活质量。材料与方法。文章介绍了眼睑脱畸形病变的临床病例,这些病例在接受类似治疗的情况下疾病结果各不相同。实验室诊断包括绘制眼尖图。用脱毛的睫毛作为检测眼睑螨虫的材料。使用光学显微镜对螨虫个体进行计数,并考虑到螨虫发育的所有形式。该研究对一年中不同时期疑似脱皮症患者的检查频率进行了统计,证实了这种疾病的季节性。文献综述包括德氏螨的研究历史数据、关于其发病机制的现有假说和理论,以及国内外治疗眼螨病的方法,包括现代硬件技术的相关信息。螨虫在睑缘炎和睑结膜炎的发病中起着重要作用。重要的是要考虑到螨虫病可能是在其他病因引起的炎症性眼病的背景下发生的。目前,眼脱皮症的治疗仍然复杂、漫长且效果不佳。在评估螨虫图结果时,任何阶段的螨虫检测结果都具有临床意义,但并非所有病例中检测到的螨虫数量与临床表现的严重程度都有直接关系。
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