The fabrication process of polydimethylsiloxane (PDMS) nanostructured films with antimicrobial properties against methicillin-resistant staphylococcus aureus (MRSA)
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引用次数: 0
Abstract
Physical topography modification is an approach to fabricate nanostructures surfaces with antimicrobial properties. Lithography-based technologies offer an effective technique to develop the desired sizes and geometry. The replica molding technique was employed to fabricate the PDMS nanostructures using the PMMA imaging layer and characterized using a FESEM and AFM. The cell viability of gram-positive bacteria on structural diminished by almost 80% and the cells were deformed and ruptured once attached to the structured surface. Thus, the PDMS structured surface enhanced the bactericidal properties of the film, which effectively inhibit bacterial attachment.
期刊介绍：
Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance.
Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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