Techniques of benzodiazepine withdrawal in clinical practice. A consensus workshop report.

J Marks
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引用次数: 10

Abstract

This is a report of a consensus conference on the management of the benzodiazepine-dependent patient. While the focus is on patients who are already dependent, it is better to avoid dependence in therapeutic use by careful patient selection, low dose and short term administration. The management of dependence can normally be undertaken in general practice unless there are complicating factors, e.g. concomitant severe medical, psychiatric or social problems. Inpatient management is also preferable for those abusing drugs in the sociorecreational area. Withdrawal should be achieved by gradual dosage reduction over a period of several weeks. Support from the practitioner, family and friends is important to achieve good results. Since postwithdrawal problems occur, good clinician support is necessary over at least the next year. Despite the risk of dependence, it is stressed that benzodiazepines are valuable therapeutic agents for several psychiatric and physical disorders.

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苯二氮卓类药物在临床中的停药技术。协商一致的研讨会报告。
这是一份关于苯二氮卓类药物依赖患者管理的共识会议报告。虽然重点是已经依赖的患者,但在治疗使用中最好通过仔细选择患者,低剂量和短期给药来避免依赖。除非有复杂的因素,例如伴随严重的医疗、精神或社会问题,否则通常可以在一般实践中对依赖进行管理。对于那些在社会娱乐场所滥用药物的人,住院治疗也是可取的。停药应在几周内逐渐减少剂量。来自医生、家人和朋友的支持对于取得好的效果很重要。由于停药后出现问题,至少在接下来的一年里,良好的临床医生支持是必要的。尽管存在依赖的风险,但需要强调的是,苯二氮卓类药物对几种精神和身体疾病是有价值的治疗药物。
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Poisoning due to class 1B antiarrhythmic drugs. Lignocaine, mexiletine and tocainide. Fulminant hyperkalaemia and multiple complications following ibuprofen overdose. Problems and pitfalls in the use of hyperbaric oxygen for the treatment of poisoned patients. A prolonged QTc interval. Is it an important effect of antiarrhythmic drugs? Clinical features and management of poisoning due to potassium chloride.
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