Stacy L Pelekhaty, Mehrnaz Pajoumand, Maureen Scarboro, Rosemary Kozar
{"title":"The Effect of Oxandrolone on Weight Loss and Muscle Mass in Acute Spinal Cord Injury Patients","authors":"Stacy L Pelekhaty, Mehrnaz Pajoumand, Maureen Scarboro, Rosemary Kozar","doi":"10.1097/tin.0000000000000353","DOIUrl":null,"url":null,"abstract":"To investigate the impact of oxandrolone on weight and lean body mass (LBM) loss after acute spinal cord injury (aSCI), this observational study compared patients who received oxandrolone with historical controls. Age, sex, injury level, admission and discharge anthropometrics, nutrition interventions, length of stay, liver function tests, sternocleidomastoid muscle area (SMA) indexed to height on admission, and follow-up computed tomography scans were collected. Twenty patients receiving oxandrolone and 20 controls were included. Oxandrolone patients lost less weight; however, no differences were observed in SMA. Oxandrolone reduced weight loss following aSCI, but larger studies are needed to assess its impact on LBM.","PeriodicalId":48681,"journal":{"name":"Topics in Clinical Nutrition","volume":null,"pages":null},"PeriodicalIF":0.4000,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Topics in Clinical Nutrition","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/tin.0000000000000353","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"NUTRITION & DIETETICS","Score":null,"Total":0}
引用次数: 0
Abstract
To investigate the impact of oxandrolone on weight and lean body mass (LBM) loss after acute spinal cord injury (aSCI), this observational study compared patients who received oxandrolone with historical controls. Age, sex, injury level, admission and discharge anthropometrics, nutrition interventions, length of stay, liver function tests, sternocleidomastoid muscle area (SMA) indexed to height on admission, and follow-up computed tomography scans were collected. Twenty patients receiving oxandrolone and 20 controls were included. Oxandrolone patients lost less weight; however, no differences were observed in SMA. Oxandrolone reduced weight loss following aSCI, but larger studies are needed to assess its impact on LBM.
期刊介绍：
Topics in Clinical Nutrition (TICN) is a peer-reviewed, quarterly journal designed as a resource for the continuing education and clinical practice of dietitians and nutritionists. Each issue addresses topics of interest primarily to dietitians and nutritionists, students and interns in professional training programs and other health care personnel involved in the nutritional care of patients. Articles include translational research reports (work that applies new knowledge to practical effect), practice projects, evidence-based literature reviews, case studies and book reviews, and articles that highlight education theory and applied research which share the tools and techniques of nutrition and dietetics education.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
