Efficacy of prenatal care in preventing congenital syphilis: a retrospective longitudinal analysis in Araçatuba, São Paulo

Damaris Rodrigues da Conceição, Ligia Arabe Lima, Laura Mendes Guedes, Letícia Cazarré Nascimento, Julia Carvalho de Souza, Nathália de Oliveira Cardoso
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Abstract

Introduction: Congenital syphilis stands as one of the primary causes of abortion worldwide, presenting a public health challenge in Brazil, where its incidence has been on the rise for the past 10 years, despite its preventable nature. Aim: To assess the effectiveness of prenatal care in averting congenital syphilis and mitigating adverse complications for newborns. Design: An observational, longitudinal, retrospective study was conducted, involving 65 newborns with congenital syphilis and their respective mothers. Data were gathered from the Notifiable Diseases Information System of Araçatuba-SP, spanning from 2018 to 2021. Results: A significant correlation was observed between attendance of prenatal care and neonatal outcomes. It was discovered that delayed diagnosis of infection in pregnant women was linked to more severe clinical manifestations in newborns. While only 13.7% of infants born to mothers diagnosed during prenatal care exhibited early symptoms, this figure rose to 57.1% in cases where diagnosis occurred during delivery. Implications: Despite endeavors to eradicate congenital syphilis, the persistent uptick in its incidence indicates deficiencies in prenatal care, underscoring the urgent necessity for interventions in primary healthcare.
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产前护理在预防先天性梅毒方面的功效:圣保罗州阿拉萨图巴的回顾性纵向分析
导言:先天性梅毒是导致全球流产的主要原因之一,也是巴西公共卫生面临的一项挑战,尽管梅毒是可以预防的,但其发病率在过去十年中一直呈上升趋势。目的:评估产前护理在避免先天性梅毒和减轻新生儿不良并发症方面的效果。设计:进行一项观察性、纵向、回顾性研究,涉及65名患有先天性梅毒的新生儿及其母亲。数据收集自阿拉萨图巴-南太平洋的应申报疾病信息系统,时间跨度为2018年至2021年。结果显示产前护理与新生儿预后之间存在明显的相关性。研究发现,孕妇感染诊断延迟与新生儿更严重的临床表现有关。在产前检查中被确诊的母亲所生的婴儿中,只有 13.7% 表现出早期症状,而在分娩过程中被确诊的病例中,这一数字上升到了 57.1%。影响:尽管人们一直在努力根除先天性梅毒,但梅毒发病率的持续上升表明产前护理存在缺陷,因此迫切需要在初级医疗保健中采取干预措施。
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