Analytical Study of Pippalyadigana Vati - An Ayurvedic Formulation

Priyanka Dubey, Renu Rao, Gunjan Sharma, Aditi
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Abstract

In Ayurveda, the raw drugs are classified under various groups known as Gana, which contain substances with comparable qualities that can treat a particular ailment. Ganas are very crucial to making the treatment field simpler and more efficient. Acharya Sushrut made a truly remarkable contribution by classifying the drugs into 37 distinct categories for various ailments. Pippalyadi gana is one of the Ganas described by Acharya Sushruta and is specially mentioned for the management of Pratishyaya. Pratishyaya is one important disease of Urdhwajatrugata Roga. In Ayurveda, Kalka, Kawath, Churna and Vati are the most frequently used form of medication. Vati preparation is considered a secondary Kashaya Kalpana and offers an easy way to administer oral medication. In the present study, 14 drugs from Pippalyadi Gana were selected for Vati preparation and certain of them were used in Kwath form for Bhavna, while the drugs containing volatile oils were utilized in powder form. Vati Kalpana has been prepared according to general method of preparation Vati mentioned in API. Prepared Vati were tested by many parameters including physical and chemical ones, such as weight variation and disintegration time, and chromatographic tests, such as TLC fingerprinting, were used to standardize it. After the testing, all parameters were found to be within API standard limits. This kind of result indicates a good therapeutic property of Vati Kalpana which can be used as oral medication for Pratishyaya.
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阿育吠陀配方 Pippalyadigana Vati 的分析研究
在阿育吠陀中,生药被归入不同的组别,称为 "伽纳"(Gana),其中包含的物质具有可比性,可以治疗特定的疾病。伽纳对于简化治疗过程、提高治疗效率至关重要。阿查里亚-苏斯鲁特将药物分为 37 个不同的类别,用于治疗各种疾病,做出了真正卓越的贡献。Pippalyadi gana 是 Acharya Sushruta 描述的 Ganas 之一,专门用于治疗 Pratishyaya。Pratishyaya 是 Urdhwajatrugata Roga 的一种重要疾病。在阿育吠陀中,Kalka、Kawath、Churna 和 Vati 是最常用的药物。Vati 制剂被认为是次级 Kashaya Kalpana,提供了一种简便的口服药物。在本研究中,从 Pippalyadi Gana 中挑选了 14 种药物用于 Vati 制剂,其中一些以 Kwath 形式用于 Bhavna,而含有挥发油的药物则以粉末形式使用。Vati Kalpana 是根据 API 中提到的一般 Vati 制备方法制备的。对制备的 Vati 进行了多项参数测试,包括重量变化和崩解时间等物理和化学参数,并使用 TLC指纹图谱等色谱测试对其进行标准化。经检测,所有参数均在原料药标准范围内。这种结果表明 Vati Kalpana 具有良好的治疗特性,可用作 Pratishyaya 的口服药物。
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