Estimulación del ganglio de Gasser para dolor neuropático del trigémino refractario

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Abstract

Background and objective

Painful trigeminal neuropathy is a complex clinical entity due to its severity and refractoriness to pharmacological and interventional management. We describe our experience in treating refractory painful trigeminal neuropathy (RPTN) with Gasserian ganglion stimulation (GGS).

Materials and methods

Six patients with RPTN were treated with GGS in our unit between 2019 and 2022. The following data were collected: socio-demographic characteristics, triggering event, duration of the disease and treatment received prior to surgery, pre- and post-intervention visual analogue scale score, follow-up time, and pre- and post-intervention functionality and quality of life.

Results

All patients were women who had received aggressive first-, second-, and third-line pharmacological, non-pharmacological, and interventional management before being referred for GGS. Patients reported a 50-72% decrease in pain on visual analogue scale and improved functionality during follow-up.

Conclusions

GGS is a promising therapeutic alternative for patients with RPTN. Although the initial outcomes and experience are encouraging, RPTN is recommended on the basis of safety, reproducibility, and trends observed in clinical practice.

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刺激加瑟神经节治疗难治性三叉神经痛
背景和目的疼痛性三叉神经病变是一种复杂的临床实体,因为其严重性和对药物和介入治疗的耐受性。我们介绍了本单位在 2019 年至 2022 年期间使用 GGS 治疗难治性疼痛性三叉神经病(RPTN)的经验。收集了以下数据:社会人口学特征、诱发事件、病程和术前接受的治疗、干预前后的视觉模拟量表评分、随访时间以及干预前后的功能和生活质量。结果所有患者均为女性,在转诊接受 GGS 治疗之前,她们已接受了积极的一线、二线和三线药物、非药物和介入治疗。随访期间,患者的视觉模拟量表显示疼痛减轻了 50%-72% 并改善了功能。虽然最初的结果和经验令人鼓舞,但基于安全性、可重复性和临床实践中观察到的趋势,建议采用 RPTN。
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来源期刊
CiteScore
1.80
自引率
15.40%
发文量
113
审稿时长
82 days
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