The Role of Tissue Engineering and Three-Dimensional–Filled Conduits in Bridging Nerve Gaps: A Review of Recent Advancements

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引用次数: 0

Abstract

Tissue-engineered nerve guidance conduits (NGCs) are an area of research interest and investment. Currently, two separate three-dimensional, filled NGCs have Food and Drug Administration approval in the management of nerve gaps up to 3 cm in length, with more on the horizon. Future NGC options will leverage increasingly intricate designs to mimic the natural biology and architecture of native nerve tissue. To enhance the development of next-generation NGCs, experimental protocols and models should be standardized. For the NGCs currently on the market, more clinical data and randomized comparative studies are needed.

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组织工程和三维填充导管在弥合神经间隙中的作用:最新进展综述
组织工程神经引导导管(NGC)是一个备受关注和投资的研究领域。目前,两种独立的三维填充 NGC 已获得美国食品药品管理局批准,用于治疗长度达 3 厘米的神经间隙,还有更多的 NGC 即将问世。未来的 NGC 选择将利用越来越复杂的设计来模仿天然神经组织的自然生物学和结构。为了促进下一代 NGC 的开发,实验方案和模型应该标准化。对于目前市场上的 NGC,还需要更多的临床数据和随机对比研究。
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1.10
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0.00%
发文量
111
审稿时长
12 weeks
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