Differences And Different Responses In Inflammation And Pneumonia (A Mini Review)

Yulia Putri, Dina Keumala Sari, Yunita Sari Pane, Ririe Fachrina Malisie, Nuraiza Meutia, M. Ichwan
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Abstract

A major public health issue with high morbidity and short and long term mortality in all age groups worldwide, pneumonia is a typical acute respiratory infection that affects the alveoli and distal airways. Community-acquired pneumonia and hospital-acquired pneumonia are the two main categories of pneumonia. Pneumonia can be brought on by a wide range of microbes, including bacteria, respiratory viruses, and fungus. The incidence of these microbes varies greatly geographically. Pneumonia affects susceptible people more frequently, such as young children under the age of five and older persons with a history of chronic illnesses. Pathogen features play a less important influence in disease development than does the host immune response. Patients with pneumonia frequently exhibit respiratory and systemic symptoms, and radiological findings as well as clinical presentation are used to make the diagnosis. It is essential to identify the microorganisms that are causing the disease because delayed or ineffective antimicrobial therapy can have negative effects. The treatment of pneumonia will be enhanced by new antibiotic and non-antibiotic medicines, as well as quick and precise diagnostic tools that can identify bacteria and drug resistance.
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炎症和肺炎的差异与不同反应(微型综述)
肺炎是一种典型的急性呼吸道感染,会影响肺泡和远端气道,是一个重大的公共卫生问题,在全球各年龄组中发病率和短期及长期死亡率都很高。肺炎分为社区获得性肺炎和医院获得性肺炎两大类。肺炎可由多种微生物引起,包括细菌、呼吸道病毒和真菌。这些微生物的发病率因地域而有很大差异。肺炎多发于易感人群,如五岁以下幼儿和有慢性病史的老年人。与宿主的免疫反应相比,病原体的特征对疾病发展的影响较小。肺炎患者经常表现出呼吸道和全身症状,诊断时需要结合放射学检查结果和临床表现。确定致病微生物至关重要,因为抗菌治疗延误或无效会产生负面影响。新的抗生素和非抗生素药物,以及能够识别细菌和耐药性的快速、精确的诊断工具,都将促进肺炎的治疗。
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