Identification of Medicinal Chemicals (BKO) Piroxicam in Jamu Pegal Linu Preparations in Makassar City

Hydrogen: Jurnal Kependidikan Kimia Pub Date : 2024-02-29 DOI:10.33394/hjkk.v12i1.10576

Hasnaeni Hasnaeni, Selpida Handayani, Velda Andina

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Abstract

The aim of the research was to identify Piroxicam in herbal medicine for rheumatic pain circulating in Makassar. There are several traditional medicines that contain medicinal chemicals. Research has been conducted on the identification of medicinal chemicals (BKO) on several rheumatic herbs preparations in herbs shops in Makassar. The BKO which is often included in rheumatic herbs is the NSAID group, one of which is piroxicam. This inspection was conducted to know the presence of the chemical drug piroxicam contained within rheumatic herbs preparations and the samples used were 5 samples. The method used was a qualitative test using thin layer chromatography (TLC) consisting of a mobile phase mixed with n-hexane and acetone (7:3) and a stationary phase using Silica Gel GF254. The results of the TLC examination from 5 samples of herbal medicine added BKO piroxicam contained 3 samples including herbs A, B, and C because they had the same stain color at the same Rf value as the piroxicam. Some of the rheumatic herbs circulating in Makassar contain medicinal chemicals in the form of piroxicam.

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鉴定望加锡市 Jamu Pegal Linu 制剂中的药用化学品 (BKO) 吡罗昔康

这项研究的目的是找出马卡萨市流传的治疗风湿痛的草药中的吡罗昔康。有几种传统药物含有药用化学物质。已对望加锡草药店中几种风湿草药制剂的药用化学物质（BKO）进行了鉴定研究。风湿草药中经常含有的 BKO 是非甾体类抗炎药，其中一种是吡罗昔康。这次检查的目的是了解风湿草药制剂中是否含有化学药物吡罗昔康，共使用了 5 个样本。采用的方法是薄层色谱法（TLC）定性检测，流动相为正己烷和丙酮（7:3）混合液，固定相为硅胶 GF254。5 份添加了 BKO 吡罗昔康的中药样品的 TLC 检验结果显示，包括药材 A、B 和 C 在内的 3 份样品与吡罗昔康的 Rf 值相同，具有相同的染色颜色。在望加锡流通的一些风湿草药中含有吡罗昔康形式的药用化学物质。

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Hydrogen: Jurnal Kependidikan Kimia

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