Carbon nanotubes as neuroprotective agents

Daisy L. Wilson, J. Ahlawat, Mahesh Narayan
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Abstract

Carbon nanotubes, an emerging class of carbon nanomaterials, possess tremendous potential for application in biotechnology and biomedicine particularly in neurological disorders. Carbon nanotubes owing to their fascinating properties have the potential to revolutionize medicine and technology, particularly in the realm of drug delivery, biosensing, bioimaging, and as therapeutic agents to tackle complex neurological disorders such as Alzheimer’s and Parkinson’s disease. In this review, a summary of the use of carbon nanotubes for neuropathological outcomes such as alleviating oxidative stress and amyloid formation, which are well-studied molecular outcomes associated with Alzheimer’s and Parkinson’s disease. In the end, challenges associated with the clinical testing of carbon nanotubes and possible ways to overcome them are highlighted.
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作为神经保护剂的碳纳米管
碳纳米管是一类新兴的碳纳米材料,在生物技术和生物医学领域具有巨大的应用潜力,尤其是在神经系统疾病方面。碳纳米管由于其迷人的特性,有可能给医学和技术带来革命性的变化,尤其是在药物输送、生物传感、生物成像领域,以及作为治疗剂来应对阿尔茨海默氏症和帕金森氏症等复杂的神经系统疾病方面。本综述总结了碳纳米管在神经病理学方面的应用,如减轻氧化应激和淀粉样蛋白的形成,这些都是与阿尔茨海默氏症和帕金森氏症相关的分子结果,已被充分研究。最后,重点介绍了与碳纳米管临床试验相关的挑战以及克服这些挑战的可能方法。
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