BioModels’ Model of the Year 2023

Rahuman S. Malik Sheriff, Hiroki Asari, Henning Hermjakob, Wolfgang Huber, Thomas Quail, Silvia D. M. Santos, Amber M. Smith, Virginie Uhlmann
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Abstract

Mathematical modeling is a pivotal tool for deciphering the complexities of biological systems and their control mechanisms, providing substantial benefits for industrial applications and answering relevant biological questions. BioModels’ Model of the Year 2023 competition was established to recognize and highlight exciting modeling-based research in the life sciences, particularly by non-independent early-career researchers. It further aims to endorse reproducibility and FAIR principles of model sharing among these researchers. We here delineate the competition’s criteria for participation and selection, introduce the award recipients, and provide an overview of their contributions. Their models provide crucial insights into cell division regulation, protein stability, and cell fate determination, illustrating the role of mathematical modeling in advancing biological research.
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生物模型公司的 2023 年模型
数学建模是破译复杂的生物系统及其控制机制的关键工具,为工业应用和回答相关生物问题带来了巨大益处。BioModels 的 "2023 年度模型 "竞赛旨在表彰和突出生命科学领域令人振奋的建模研究,尤其是非独立的早期职业研究人员的研究。它还旨在认可这些研究人员之间模型共享的可复制性和 FAIR 原则。我们在此阐述了竞赛的参赛和评选标准,介绍了获奖者,并概述了他们的贡献。他们的模型为细胞分裂调控、蛋白质稳定性和细胞命运决定提供了重要见解,说明了数学建模在推动生物研究方面的作用。
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