Preeclampsia at Term Can Be Classified Into Two Clusters With Different Clinical Characteristics and Outcomes Based on Angiogenic Biomarkers in Maternal Blood

T. Chaiworapongsa, R. Romero, F. Gotsch, M. Suksai, D.M. Gallo, E. Jung, A. Krieger, P. Chaemsaithong, O. Erez, A. Tarca
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Abstract

(Am J Obstet Gynecol. 2023;228:569.e1–569.e24) Pre-eclampsia, a complex and multisystemic disorder affecting a significant percentage of pregnancies worldwide, is a leading cause of preterm birth and maternal mortality. This condition is not uniform and can be classified into different subtypes based on gestational age and underlying pathophysiological mechanisms. Understanding these subtypes is crucial for predicting maternal and fetal outcomes and developing targeted therapeutic strategies.
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根据母体血液中的血管生成生物标记物,足月子痫前期可分为临床特征和预后不同的两个群组
(Am J Obstet Gynecol. 2023;228:569.e1-569.e24)子痫前期是一种复杂的多系统疾病,影响着全球相当大比例的妊娠,是早产和孕产妇死亡的主要原因。这种疾病并不统一,可根据妊娠年龄和潜在的病理生理机制分为不同的亚型。了解这些亚型对于预测孕产妇和胎儿的预后以及制定有针对性的治疗策略至关重要。
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