Evaluating the Therapeutic Efficacy of L-Lysine Aescinat Supplementation on Neurological Outcomes in Patients with Spinal Fractures and Traumatic Spine Injuries: A Prospective Cohort Study from Tbilisi, Georgia

Koka Gogichashvili, Zviad Malazonia, Tornike Kldiashvili, Ciara Francesca Maxwell
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Abstract

This prospective study aimed to comprehensively investigate the impact of L-Lysine aescinat supplementation on the neurological outcomes of patients recovering from spinal fractures and traumatic spine injuries. A total of 32 patients were recruited and categorised into two groups: Group A (n=16), receiving L-Lysine aescinat supplementation, and Group B (N=16), serving as the control group without L-Lysine aescinat administration. The primary objective was to assess changes in the Karnofsky performance scale, a functional and well-being neurological assessment tool especially for those undergoing operations or with chronic illness, over a follow up period of one month in order to determine if L-Lysine aescinat had an immediate effect on recovery in the post-operative period. Urinary dysfunction was noted, alongside the location of the fracture, type of surgery and if there were any significant comorbidities.
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评估补充 L-Lysine Aescinat 对脊柱骨折和脊柱外伤患者神经功能结果的疗效:格鲁吉亚第比利斯前瞻性队列研究
这项前瞻性研究旨在全面探讨补充 L-赖氨酸 aescinat 对脊柱骨折和脊柱外伤康复患者神经功能预后的影响。研究共招募了 32 名患者,并将其分为两组:A 组(16 人)接受 L-赖氨酸 aescinat 补充剂,B 组(16 人)作为对照组,不服用 L-赖氨酸 aescinat。主要目的是评估卡诺夫斯基表现量表在一个月随访期间的变化,以确定赖氨酸麦角脂是否对术后恢复有立竿见影的效果。卡诺夫斯基表现量表是一种功能和健康神经评估工具,尤其适用于接受手术或患有慢性疾病的患者。除了骨折部位、手术类型以及是否有重大并发症外,还记录了排尿功能障碍情况。
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