Issues of contraception in rheumatic diseases: current status of the problem and perspectives

T. S. Panevin, A. Smetnik, T. Dubinina
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Abstract

Contraception is an important aspect of reproductive health in patients with rheumatic diseases. This is primarily due to the fact that in most immuneinflammatory rheumatic diseases (IRD) pregnancy must be planned. On one hand, the presence and activity of IRD can influence the course of the pregnancy, but on the other hand, pregnancy, which is accompanied by changes in general hormonal levels, is often a factor that alters the activity of IRD. Some patients take medication with potentially teratogenic effects. Planning a pregnancy during IRD can contribute to its optimal progression and minimize the risks of exacerbation of IRD. Given the wide range of barrier and hormonal contraceptives currently in use and the introduction of new drugs into clinical practice, data on the possibility of their use are of particular importance to rheumatologists in practical healthcare.
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风湿病的避孕问题:问题的现状和前景
避孕是风湿病患者生殖健康的一个重要方面。这主要是因为大多数免疫炎症性风湿病(IRD)患者必须计划怀孕。一方面,IRD 的存在和活性会影响妊娠的进程,另一方面,伴随着一般激素水平变化的妊娠往往也是改变 IRD 活性的一个因素。有些患者服用的药物可能具有致畸作用。在 IRD 期間計劃懷孕有助於病情的最佳發展,並將 IRD 惡化的風險降至最低。鉴于目前使用的阻隔避孕药和激素避孕药种类繁多,而且新药不断被引入临床实践,因此有关使用这些药物的可能性的数据对风湿病医生的实际医疗保健工作尤为重要。
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