Role of pretty nanoflowers as novel versatile analytical tools for sensing in biomedical and bioanalytical applications

Şeyma Dadı, I. Ocsoy
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Abstract

In recent years, an encouraging breakthrough in the synthesis of immobilized enzymes in flower‐shaped called “organic‐inorganic hybrid nanoflowers (hNFs)” with greatly enhanced catalytic activity and stability were reported. Although, these hNFs were discovered by accident, the enzymes exhibited highly enhanced catalytic activities and stabilities in the hNFs compared with the free and conventionally immobilized enzymes. Herein, we rationally utilized the catalytic activity of the hNFs for analytical applications. In this comprehensive review, we covered the design and use of the hNFs as novel versatile sensors for electrochemical, colorimetric/optical and immunosensors‐based detection strategies in analytical perspective.
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漂亮纳米花作为新型多功能分析工具在生物医学和生物分析应用中的传感作用
近年来,在合成固定化酶的花形 "有机-无机杂化纳米花(hNFs)"方面取得了令人鼓舞的突破,其催化活性和稳定性大大增强。虽然这些 hNFs 是偶然发现的,但与游离和传统固定的酶相比,hNFs 中的酶表现出更高的催化活性和稳定性。在此,我们合理地将 hNFs 的催化活性用于分析应用。在这篇综述中,我们从分析的角度探讨了 hNFs 作为新型多功能传感器在电化学、比色/光学和基于免疫传感器的检测策略中的设计和应用。
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