Iman Dandapath, Saumya Sahu, Supriya Bhardwaj, T. Mohan, Rituparna Chakraborty, Jyotsna Singh, Swati Singh, Ajay Garg, Deepak Gupta, M. Sharma, V. Suri
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引用次数: 0
Abstract
Diffuse midline gliomas are malignant tumors primarily affecting children and are associated with poor outcomes. The 2021 WHO classification introduces three subtypes that all exhibit the universal phenomenon of H3K27 trimethylation loss. In this report, we present two cases of DMG, EGFR mutant, each featuring novel EGFR mutations within exon 20. These findings contribute to a deeper understanding of the molecular characteristics of these complex pediatric brain tumors. Notably, both cases were detected using cost-effective diagnostic approaches.
期刊介绍：
ACS Applied Bio Materials is an interdisciplinary journal publishing original research covering all aspects of biomaterials and biointerfaces including and beyond the traditional biosensing, biomedical and therapeutic applications.
The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrates knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important bio applications. The journal is specifically interested in work that addresses the relationship between structure and function and assesses the stability and degradation of materials under relevant environmental and biological conditions.
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