​​The Frequency of Gangrenous Infarction of Intestine in Patients Undergoing Intestinal Resection at Tertiary Care Hospital, Rawalpindi

Mehak Ruqia, Khizra Waheed, Maimoona Maheen, Aamna Nazir, Aqiba Malik, Muhammad Sheraz Hameed, Ali Haider, Abdullah Asghar, Abdur Rehman, Sarah Arshad
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Abstract

Gangrenous bowel or dead bowel most often occurs as a result of hernia, adhesions, and mesenteric insufficiency. Intestinal gangrene due to acute mesenteric vascular events requiring surgery is one of the most common surgical emergencies at tertiary care hospitals. Objective: To determine the frequency of gangrenous infarction in patients undergoing intestinal resection at a tertiary care hospital. Methods: This descriptive cross-sectional study was conducted in the Department of Surgery and Pathology, Rawalpindi, Pakistan. A total of 140 resected intestinal specimens were included in this study. Data were entered and analyzed using SPSS v. 23. o. Descriptive statistics were applied and a P-value <0.05 was taken as statistically significant. Results: Out of 140 samples, clinical specimens from 30(21.4%) patients were found to be gangrenous. The frequency of gangrene was slightly higher in females 16 (53.3%) as compared to males 14 (46.7%) with a peak of 19 patients (63.3%) in the age group of 31 to 60 years and mostly affecting the small intestine 21 (70%). Among the total of 110 (78.6%) non-gangrenous specimens; mild inflammatory changes, perforation, ulceration, tumors, mucosal and mural infarction, infection, reactive hyperplasia, and autolytic changes were noted. Conclusions: The frequency of intestinal gangrene is much higher in our population than in most regions of the world, slightly more common in females as compared to males with a peak in the age group of 31 to 60 years and mostly involving the small intestine, indicating negligence towards this important problem. 
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拉瓦尔品第三级医院肠切除术患者肠坏疽性梗死的发生率
肠坏疽或肠坏死最常见的原因是疝气、粘连和肠系膜功能不全。急性肠系膜血管事件导致的肠坏疽需要手术治疗,这是三级医院最常见的外科急症之一。研究目的确定在一家三级医院接受肠切除术的患者中发生坏疽性梗死的频率。方法:这项描述性横断面研究在巴基斯坦拉瓦尔品第的外科和病理科进行。本研究共纳入 140 份切除的肠道标本。数据使用 SPSS v. 23.o 进行输入和分析。采用描述性统计,P 值小于 0.05 为具有统计学意义。结果在 140 份样本中,有 30 名(21.4%)患者的临床样本被发现有坏疽。与男性 14 例(46.7%)相比,女性 16 例(53.3%)的坏疽发生率略高,其中 19 例(63.3%)患者的年龄在 31 岁至 60 岁之间,主要累及小肠 21 例(70%)。在总共 110 份(78.6%)非坏死标本中,发现了轻度炎症变化、穿孔、溃疡、肿瘤、粘膜和壁层梗死、感染、反应性增生和自溶变化。结论是在我国,肠坏疽的发病率远高于世界上大多数地区,女性略高于男性,高发年龄段为 31 岁至 60 岁,且主要累及小肠,这表明人们忽视了这一重要问题。
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