The emerging role of sentinel lymph node biopsy in oral cavity and oropharyngeal carcinomas

Kimberly Chan, Mohamad Saltagi, Karen Y. Choi
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Abstract

Management of clinically negative necks (cN0) in oral cavity (OCSCC) and oropharyngeal (OPSCC) squamous cell carcinoma (SCC) has evolved over time. Historically, the clinically negative neck has been managed with elective neck dissection (END) or observation, but more recently sentinel lymph node biopsy (SLNB) has emerged as a technique to detect occult metastases. In this review, we will discuss the role of SLNB in early-stage OCSCC and in the management of OPSCC.
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前哨淋巴结活检在口腔癌和口咽癌中的新作用
口腔(OCSCC)和口咽(OPSCC)鳞状细胞癌(SCC)临床阴性颈部(cN0)的处理方法随着时间的推移而不断变化。从历史上看,临床阴性颈部肿瘤一直是通过选择性颈部切除术(END)或观察来处理的,但最近前哨淋巴结活检(SLNB)已成为一种检测隐匿性转移的技术。在本综述中,我们将讨论 SLNB 在早期 OCSCC 和 OPSCC 治疗中的作用。
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