Multiple myeloma in the mandible mimicking a radicular cyst: A case report and literature review

Y. Shimada, Hideki Miyazaki, Akira Hangaishi, Yutaka Maruoka
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Abstract

Multiple myeloma (MM) is a hematopoietic malignancy characterized by monoclonal plasma cell proliferation. Mandibular involvement in patients with MM is rare, and its clinical and radiological characteristics remain unclear.A 78‐year‐old man presented with MM in the mandible, mimicking a radicular cyst. Chemotherapy yielded a poor prognosis, and the patient died 1.5 years post‐diagnosis. Literature suggests that jawbone involvement of MM is a poor prognostic factor.This report highlights the features of MM in the jawbone, and its variable manifestation, which may include non‐neoplastic findings, thus emphasizing the importance of a definitive biopsy‐based diagnosis.
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下颌骨多发性骨髓瘤模仿放射性囊肿:病例报告和文献综述
多发性骨髓瘤(MM)是一种以单克隆浆细胞增殖为特征的造血恶性肿瘤。多发性骨髓瘤患者下颌骨受累的情况很少见,其临床和放射学特征仍不清楚。化疗预后不佳,患者在确诊后1.5年去世。文献表明,MM累及颌骨是一个不良预后因素。本报告强调了颌骨MM的特征及其多变的表现,其中可能包括非肿瘤性发现,因此强调了基于活检的明确诊断的重要性。
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