MATHEMATICAL MODELING OF THE SPREAD OF VECTOR BORNE DISEASES WITH INFLUENCE OF VERTICAL TRANSMISSION AND PREVENTIVE STRATEGIES

W. Atokolo, Remigius Okeke Aja, D. Omale, Roselyn V. Paul, Jeremiah Amos, Shedrach Onu Ocha
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Abstract

This work is aimed at formulating a mathematical model of the spread of vector-borne diseases with influence of vertical transmission and preventive strategies. Vector borne diseases are caused by viruses, bacteria, and parasites typically conveyed by mosquitoes. Certain illnesses transmitted by vectors include West Nile Virus, Malaria, Zika virus, Dengue fever, Rift valley fever, and Viral encephalitis induced by pathogens like bacteria, viruses, and parasites. The positive solutions of the model are presented and the theory of basic reproduction number  was used to study the model dynamical behaviour. When reduces; the diseases are wiped out of the population with time and vice versa. The disease free and endemic equilibria states of the model were determined and investigated to be locally and globally stable.We incorporated the use of Insecticide –Treated Nets (ITN), Indoor Residual Sprayings (IRS) and condom usage as preventive measures in the presence of treatment. Numerical simulations show that complete intervention measures, that is, the use of ITN, IRS and condom usage while placing the infected on treatment have valuable impact on the spread of vector-borne diseases.
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病媒传染病传播的数学模型与垂直传播和预防策略的影响
这项工作旨在建立一个病媒传播疾病传播的数学模型,其中包括垂直传播的影响和预防策略。病媒传播的疾病由病毒、细菌和寄生虫引起,通常由蚊子传播。由病媒传播的疾病包括西尼罗河病毒、疟疾、寨卡病毒、登革热、裂谷热以及由细菌、病毒和寄生虫等病原体诱发的病毒性脑炎。提出了模型的正解,并利用基本繁殖数理论研究了模型的动态行为。当减少时,疾病会随着时间从种群中消灭,反之亦然。我们将使用驱虫蚊帐(ITN)、室内滞留喷洒(IRS)和使用安全套作为治疗时的预防措施。数值模拟显示,完全干预措施,即使用驱虫蚊帐、室内滞留喷洒和使用安全套,同时让感染者接受治疗,对病媒传播疾病的传播有重要影响。
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