Sudesh Kumari, Prity Gulia, Pooja Choudhary, N. Sharma, Sweety Dahiya, Aruna Punia, A. K. Chhillar
{"title":"Endophytes: Untapped Source of Antifungal Agents","authors":"Sudesh Kumari, Prity Gulia, Pooja Choudhary, N. Sharma, Sweety Dahiya, Aruna Punia, A. K. Chhillar","doi":"10.2174/0115734072276049231207110314","DOIUrl":null,"url":null,"abstract":"\n\nScreening for novel bioactive compounds has become more critical since drugresistant\nfungal infections have emerged and ethno-medicinal plants have been embarked as antifungal\nagents. The emphasis on medicinal plants has recently switched to the study of endophytes\nand their interactions with the host plant and screening of their antifungal activity. Endophytes\nare an endosymbiotic group of microorganisms that thrive within plant tissues without causing\nany symptoms or marking their presence. Endophytes have been looked into as potential resources\nfor producing distinctive bioactive substances. The quest for bioactive natural compounds\nof endophytes isolated from higher plants is receiving a lot of interest from researchers worldwide,\nas seen by the recent surge in studies and publications on antifungal potential. This review\naims to comprehend the role and applications of endophytes as a promising source of antifungal\nagents and enlighten on their most common mode of action.\n","PeriodicalId":10772,"journal":{"name":"Current Bioactive Compounds","volume":"67 3","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Bioactive Compounds","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/0115734072276049231207110314","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Pharmacology, Toxicology and Pharmaceutics","Score":null,"Total":0}
引用次数: 0
Abstract
Screening for novel bioactive compounds has become more critical since drugresistant
fungal infections have emerged and ethno-medicinal plants have been embarked as antifungal
agents. The emphasis on medicinal plants has recently switched to the study of endophytes
and their interactions with the host plant and screening of their antifungal activity. Endophytes
are an endosymbiotic group of microorganisms that thrive within plant tissues without causing
any symptoms or marking their presence. Endophytes have been looked into as potential resources
for producing distinctive bioactive substances. The quest for bioactive natural compounds
of endophytes isolated from higher plants is receiving a lot of interest from researchers worldwide,
as seen by the recent surge in studies and publications on antifungal potential. This review
aims to comprehend the role and applications of endophytes as a promising source of antifungal
agents and enlighten on their most common mode of action.
Current Bioactive CompoundsPharmacology, Toxicology and Pharmaceutics-Pharmacology, Toxicology and Pharmaceutics (all)
CiteScore
1.90
自引率
0.00%
发文量
112
期刊介绍：
The journal aims to provide comprehensive review articles on new bioactive compounds with proven activities in various biological screenings and pharmacological models with a special emphasis on stereoeselective synthesis. The aim is to provide a valuable information source of bioactive compounds synthesized or isolated, which can be used for further development of pharmaceuticals by industry and academia. The journal should prove to be essential reading for pharmacologists, natural product chemists and medicinal chemists who wish to be kept informed and up-to-date with the most important developments on new bioactive compounds of natural or synthetic origin, including their stereoeselective synthesis.
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