Health Checks for People with Down Syndrome: A Pooled Analysis of Three Randomized Controlled Trials

Robert S. Ware, Catherine Franklin, Lyn McPherson, Nicholas G. Lennox
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Abstract

Health checks have beneficial effects on health outcomes in adults with intellectual disability; however, little is known about their effect on people with Down syndrome. The aim of this study was to assess the effect of receiving a health check on the unmet health needs of people with Down syndrome. A pooled analysis of three randomized trials conducted by the same Australian research team was undertaken. The trials used the same tools but differed by participant source (adults in 24 h supported accommodation, adults in private dwellings, adolescents living with parents). The intervention was a one-off health check, and the comparator was usual care. Among 216 participants, health actions were more likely to occur for those allocated to receive health checks, including increased hearing (odds ratio = 4.4; 95% confidence interval: 1.2, 16.4), vision (2.7; 1.1, 6.7), and thyroid (2.3; 1.3, 4.2) testing, and weight recording (4.7; 2.5, 8.8). Health checks conducted at the primary-care level produced substantially increased attention to the health needs of people with Down syndrome.
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唐氏综合症患者的健康检查:三项随机对照试验的汇总分析
健康检查对智障成人的健康状况有好处,但对唐氏综合症患者的影响却知之甚少。本研究旨在评估接受健康检查对唐氏综合症患者未满足的健康需求的影响。本研究对澳大利亚同一研究团队进行的三项随机试验进行了汇总分析。这些试验使用了相同的工具,但参与者来源不同(24 小时辅助住宿的成年人、私人住宅中的成年人、与父母同住的青少年)。干预措施是一次性的健康检查,而比较对象是常规护理。在 216 名参与者中,被分配接受健康检查的人更有可能采取健康行动,包括增加听力(几率比=4.4;95% 置信区间:1.2,16.4)、视力(2.7;1.1,6.7)和甲状腺(2.3;1.3,4.2)检测以及体重记录(4.7;2.5,8.8)。在初级保健层面进行的健康检查大大增加了对唐氏综合症患者健康需求的关注。
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