The nanoparticle formula optimization from Temulawak extract (Curcuma xanthorrhiza) as adjuvant therapy

Greesty F. Swandiny, Safira Nafisa, Rahmatul Qodriah, Gumilar Adhi Nugroho, Muhammad Taher Bakhtiar
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Abstract

Temulawak extract was synthesized using temulawak sodium alginate. The nanoparticle formula was obtained by combining the characteristics of temuwak extract and temusawak. The microbeads were characterized by scanning electron microscopy (SEM) and Fourier transform infrared (FTIR) spectroscopy. The size of Alg-Curcuma was measured at SEM. The particle size distribution of the sample was analyzed using FTIR spectra. The results showed that the size of the resulting beads is microparticle in size. It was found that the temurawak extract is a good candidate as an anticancer agent. Therefore, there are several recommendations that can be done to optimize the synthesis of the material. The study reported that the recommended parameter is 12.5 kV with a flow rate of 0.1 mL/h (first batch synthesis).
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从 Temulawak(莪术)提取物中优化纳米粒子配方作为辅助疗法
使用海藻酸钠合成了泰木拉瓦提取物。纳米粒子配方是结合了泰木拉瓦提取物和泰木拉瓦的特点而得到的。微珠通过扫描电子显微镜(SEM)和傅立叶变换红外光谱(FTIR)进行表征。扫描电子显微镜测量了 Alg-Curcuma 的大小。傅立叶变换红外光谱分析了样品的粒度分布。结果表明,所得珠子的粒度为微粒子大小。研究发现,泰木拉瓦提取物是一种很好的抗癌剂。因此,有几项建议可以优化材料的合成。研究报告指出,建议的参数为 12.5 kV,流速为 0.1 mL/h(第一批合成)。
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