Clinical encounters of giant cell fibroma: A comprehensive report on two distinct cases, exploring varied clinical presentations

Abstract

A giant-cell fibroma (GCF) is a benign, localized mucosal mass composed of fibrous tissue that exhibits clinical similarities to other fibro-epithelial growths. Its differentiation from other lesions relies on its distinctive histopathological characteristics. GCF is a rare oral fibrous lesion, often misdiagnosed as other fibrous growths. The first case involves a 24-year-old female with a GCF located near mandibular buccal gingiva. The second case centers on a 14-year-old boy who developed GCF on the incisive papilla region. These cases shed light on the diverse clinical manifestations and histopathological markers used in the diagnosis of GCF. The report delves into the clinical presentation, histological features, and differential diagnoses, offering valuable insights for oral healthcare professionals. Understanding the occurrence of GCF on different aspects of the gingiva is crucial for accurate diagnosis and effective treatment. This report contributes to the growing body of knowledge regarding this rare oral lesion and emphasizes the importance of considering GCF in the differential diagnosis of gingival growths.