Comparison of Efficacy of Amoxicillin/Clavulanate Potassium and Azithromycin Sequential Therapies on Nutritional Status of Children with Bronchopneumonia

Abstract

Bronchopneumonia is a highly prevalent respiratory disease among malnourished children and infants, and it is mainly treated with antibiotics. Herein, we compared the efficacy of amoxicillin/clavulanate potassium and azithromycin sequential therapies for bronchopneumonia. We found that amoxicillin/clavulanate potassium had improved clinical efficacy and accelerated rehabilitation in patients with bronchopneumonia. Azithromycin demonstrated superior efficacy in inhibiting inflammation, enhancing nutritional status, and regulating trace element levels. The therapeutic safety profile of the two sequential therapies was broadly consistent. In the treatment of bronchopneumonia, azithromycin and amoxicillin/clavulanate potassium have their advantages and disadvantages. Therefore, the drug selection for children should be based on their specific conditions.