COMMENTARY PART 1: EVALUATING THE ASSOCIATION OF FEMALE OBESITY WITH THE RISK OF LIVE BIRTH FOLLOWING IVF - IMPLICATIONS FOR CLINICAL PRACTICE

Emma Schneider, O. Hamer, Chris Smith, J. Hill
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Abstract

Obesity is a well-established risk factor for infertility. Consequentially, women living with obesity may require fertility treatment to support them to conceive. Due to evidence suggesting obesity is also linked with poorer outcomes following in vitro fertilisation (IVF), local commissioning guidelines on assisted conception recommend a BMI of <30kg/m2 before IVF can commence. However, it is currently unclear if these guidelines are evidence based. This commentary aims to critically appraise a recent systematic review by Sermondade, et al., (2019) and expand upon the implications of the findings for clinical practice.
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评论第 1 部分:评估女性肥胖与试管婴儿活产风险的关系--对临床实践的启示
肥胖是一个公认的不孕症风险因素。因此,肥胖妇女可能需要接受辅助受孕治疗。有证据表明,肥胖还与体外受精(IVF)的不良结果有关,因此,当地的辅助受孕委托指南建议,在开始体外受精之前,体重指数(BMI)应小于 30kg/m2。然而,目前尚不清楚这些指南是否以证据为基础。本评论旨在对 Sermondade 等人(2019 年)最近发表的一篇系统综述进行批判性评估,并阐述研究结果对临床实践的影响。
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