Cisgender cellular tissue-based products improve wound healing.

IF 17.7 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-01-01 DOI:10.25270/wnds/23151
Christina Del Pin, Amit Rao, Meaghan Coles, Manuel Beltran del Rio, Alisha Oropallo
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Abstract

Neither the CTP sex effect of female CTP derived from cryopreserved human placental membranes, nor male CTP bioengineered from living human keratinocytes and foreskin fibroblasts has been described. Healing in wounds was examined to establish the CTP sex' s role in both males and females. Cisgender CTP wounds had better closure. Overall, male PC, PC-End, and CC rates over time were better than female rates. Outcomes were affected by access, etiology, and follow-up.
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基于顺性细胞组织的产品可改善伤口愈合。
无论是从冷冻保存的人类胎盘膜中提取的雌性 CTP,还是从活体人类角质细胞和包皮成纤维细胞中生物工程提取的雄性 CTP,其 CTP 性别效应均未得到描述。为了确定 CTP 性别在男性和女性中的作用,我们对伤口愈合情况进行了研究。同性别的 CTP 伤口愈合得更好。总体而言,随着时间的推移,男性的PC、PC-End和CC率均优于女性。结果受到入路、病因和随访的影响。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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