A Highly Efficient Computational Strategy for Unraveling MicroRNA Profiles in the Aquatic Larvae of the Mosquito Disease Vector Culex quinquefasciatus

Abstract

Culex quinquefasciatus In the intricate life cycle of Culex quinquefasciatus , characterized by an aquatic phase, the mosquito undergoes key developmental stages in water bodies. The study emphasizes the significance of this aquatic environment, shedding light on the molecular intricacies of the mosquito's larvae, a pivotal aspect in the broader context of its life cycle and ecological interactions. MicroRNAs (miRNAs), the small non-coding RNA sequences, play critical roles in cell differentiation and development in insects, including processes such as moulting, behaviour, metamorphosis, embryogenesis, and insect vector-pathogen interactions. Mosquitoes are implicated as vectors of