High amniotic fluid fractalkine and MIP-1β levels are associated with intrauterine growth restriction: a prospective cohort study

IF 17.7 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-01-01 DOI:10.55730/1300-0144.5789
Ş. Pala, R. Atılgan, Nevin Ilhan
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Abstract

Background/aim: Proinflammatory chemokines have been shown to play crucial roles in implantation, spiral artery invasion, and the fetomaternal immunological response. In this context, we investigated the levels of fractalkine (CX3CL1) and chemokine CC motif ligand 4 (CCL4 or MIP-1β) in maternal serum and amniotic fluids in pregnant women with intrauterine growth restriction (IUGR). Materials and methods: This prospective cohort study was carried out at Fırat University Obstetrics Clinic between January 1, 2022 and July 1, 2022. Group
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羊水分叉蛋白和 MIP-1β 水平高与宫内生长受限有关:一项前瞻性队列研究
背景/目的:前炎症趋化因子已被证明在着床、螺旋动脉入侵和胎儿-母体免疫反应中起着至关重要的作用。在此背景下,我们研究了宫内生长受限(IUGR)孕妇的母体血清和羊水中的分叉碱(CX3CL1)和趋化因子 CC motif 配体 4(CCL4 或 MIP-1β)的水平。材料和方法:这项前瞻性队列研究于 2022 年 1 月 1 日至 2022 年 7 月 1 日在 Fırat 大学产科诊所进行。组别
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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