Sodium-fluorescein-guided awake surgery for cerebral metastases located in eloquent brain areas: technical notes and preliminary experiences

IF 17.7 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-01-01 DOI:10.55730/1300-0144.5783
Alper Türkkan, Pınar Ocak, M. Khezri, A. Bekar
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Abstract

follow-up in either group compared to their preoperative baseline scores (p = 0.374). KPS did not show a significant difference between the 2 groups at any time. Conclusion: Fluorescence-guided resection in AC for metastatic tumors in sensory, motor, and cognitive areas is a feasible, safe, and convenient technique that significantly increases GTR rates and shortens operative time compared to conventional white light surgery without fluorescence guidance. It also does not increase the incidence of postoperative complications. With the combined use of AC and NaFl, ensuring clear and visible tumor margins during surgery and controlling patients’ neurological function in real-time are possible.
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荧光素钠引导下的清醒手术治疗位于脑功能区的脑转移瘤:技术说明和初步经验
与术前基线评分相比(P = 0.374)。两组患者在任何时间的 KPS 均无明显差异。结论荧光引导下的 AC 感觉、运动和认知区域转移性肿瘤切除术是一种可行、安全和方便的技术,与无荧光引导的传统白光手术相比,它能显著提高 GTR 率并缩短手术时间。它也不会增加术后并发症的发生率。通过联合使用 AC 和 NaFl,可以确保手术过程中肿瘤边缘清晰可见,并实时控制患者的神经功能。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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