{"title":"Global post-mortem tissue donation programmes to accelerate cancer research","authors":"Christine Desmedt, Lisa A Carey","doi":"10.1038/s41568-024-00683-w","DOIUrl":null,"url":null,"abstract":"Metastatic cancer represents the main cause of death in patients with cancer. However, basic and translational research is hampered by the limited availability of metastatic samples. In this context, post-mortem tissue donation programmes represent a complementary and attractive solution. Here, we highlight the opportunities and challenges, and outline why we believe this represents a global effort. Metastatic cancer represents the main cause of death in patients with cancer, but metastasis research is hindered by the limited availability of metastatic samples. In this Comment, Desmedt and Carey highlight the opportunities and challenges of post-mortem tissue donation programmes, which represent a complementary and attractive solution to overcome many of the hurdles in metastasis research.","PeriodicalId":19055,"journal":{"name":"Nature Reviews Cancer","volume":"24 5","pages":"289-290"},"PeriodicalIF":72.5000,"publicationDate":"2024-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature Reviews Cancer","FirstCategoryId":"3","ListUrlMain":"https://www.nature.com/articles/s41568-024-00683-w","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ONCOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Metastatic cancer represents the main cause of death in patients with cancer. However, basic and translational research is hampered by the limited availability of metastatic samples. In this context, post-mortem tissue donation programmes represent a complementary and attractive solution. Here, we highlight the opportunities and challenges, and outline why we believe this represents a global effort. Metastatic cancer represents the main cause of death in patients with cancer, but metastasis research is hindered by the limited availability of metastatic samples. In this Comment, Desmedt and Carey highlight the opportunities and challenges of post-mortem tissue donation programmes, which represent a complementary and attractive solution to overcome many of the hurdles in metastasis research.
期刊介绍：
Nature Reviews Cancer, a part of the Nature Reviews portfolio of journals, aims to be the premier source of reviews and commentaries for the scientific communities it serves. The correct abbreviation for abstracting and indexing purposes is Nat. Rev. Cancer. The international standard serial numbers (ISSN) for Nature Reviews Cancer are 1474-175X (print) and 1474-1768 (online). Unlike other journals, Nature Reviews Cancer does not have an external editorial board. Instead, all editorial decisions are made by a team of full-time professional editors who are PhD-level scientists. The journal publishes Research Highlights, Comments, Reviews, and Perspectives relevant to cancer researchers, ensuring that the articles reach the widest possible audience due to their broad scope.
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