SIMPLE-seq to decode DNA methylation dynamics in single cells

IF 39.1 1区生物学 Q1 GENETICS & HEREDITY Nature Reviews Genetics Pub Date : 2024-04-12 DOI:10.1038/s41576-024-00729-7

Dongsheng Bai, Chenxu Zhu

引用次数: 0

Abstract

In this Tools of the Trade article, Dongsheng Bai and Chenxu Zhu describe SIMPLE-seq, a scalable single-cell sequencing method that simultaneously decodes the cytosine modifications 5mC and 5hmC.

Abstract Image

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

用 SIMPLE-seq 技术解码单细胞中 DNA 甲基化的动态变化

在这篇 "贸易工具"（Tools of the Trade）文章中，白东升（Dongsheng Bai）和朱晨旭（Chenxu Zhu）介绍了一种可扩展的单细胞测序方法 SIMPLE-seq，该方法可同时解码胞嘧啶修饰 5mC 和 5hmC。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Nature Reviews Genetics 生物-遗传学

CiteScore

57.40

自引率

0.50%

发文量

113

审稿时长

6-12 weeks

期刊介绍： At Nature Reviews Genetics, our goal is to be the leading source of reviews and commentaries for the scientific communities we serve. We are dedicated to publishing authoritative articles that are easily accessible to our readers. We believe in enhancing our articles with clear and understandable figures, tables, and other display items. Our aim is to provide an unparalleled service to authors, referees, and readers, and we are committed to maximizing the usefulness and impact of each article we publish. Within our journal, we publish a range of content including Research Highlights, Comments, Reviews, and Perspectives that are relevant to geneticists and genomicists. With our broad scope, we ensure that the articles we publish reach the widest possible audience. As part of the Nature Reviews portfolio of journals, we strive to uphold the high standards and reputation associated with this esteemed collection of publications.

期刊最新文献

Biobanking with genetics shapes precision medicine and global health Plant pattern recognition receptors: from evolutionary insight to engineering Genetic conflict and its resolution between the sexes Exploring biodiversity through museomics The design and engineering of synthetic genomes