{"title":"Fine tuning of the net charge alternation of polyzwitterion surfaced lipid nanoparticles to enhance cellular uptake and membrane fusion potential","authors":"Keitaro Homma, Yutaka Miura, Motoaki Kobayashi, Wanphiwat Chintrakulchai, Masahiro Toyoda, Koichi Ogi, Junya Michinishi, Tomoyuki Ohtake, Yuto Honda, Takahiro Nomoto, Hiroyasu Takemoto, Nobuhiro Nishiyama","doi":"10.1080/14686996.2024.2338785","DOIUrl":null,"url":null,"abstract":"Lipid nanoparticles (LNPs) coated with functional and biocompatible polymers have been widely used as carriers to deliver oligonucleotide and messenger RNA therapeutics to treat diseases. Poly(ethy...","PeriodicalId":21588,"journal":{"name":"Science and Technology of Advanced Materials","volume":"6 1","pages":""},"PeriodicalIF":7.4000,"publicationDate":"2024-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Science and Technology of Advanced Materials","FirstCategoryId":"88","ListUrlMain":"https://doi.org/10.1080/14686996.2024.2338785","RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MATERIALS SCIENCE, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
Lipid nanoparticles (LNPs) coated with functional and biocompatible polymers have been widely used as carriers to deliver oligonucleotide and messenger RNA therapeutics to treat diseases. Poly(ethy...
期刊介绍：
Science and Technology of Advanced Materials (STAM) is a leading open access, international journal for outstanding research articles across all aspects of materials science. Our audience is the international community across the disciplines of materials science, physics, chemistry, biology as well as engineering.
The journal covers a broad spectrum of topics including functional and structural materials, synthesis and processing, theoretical analyses, characterization and properties of materials. Emphasis is placed on the interdisciplinary nature of materials science and issues at the forefront of the field, such as energy and environmental issues, as well as medical and bioengineering applications.
Of particular interest are research papers on the following topics:
Materials informatics and materials genomics
Materials for 3D printing and additive manufacturing
Nanostructured/nanoscale materials and nanodevices
Bio-inspired, biomedical, and biological materials; nanomedicine, and novel technologies for clinical and medical applications
Materials for energy and environment, next-generation photovoltaics, and green technologies
Advanced structural materials, materials for extreme conditions.
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