Lymphangitic Melanomatosis: Case Report of Intralymphatic Spread of Melanoma in a 66-year-old Man.

Shantanu Srivatsa, Collin-Jamal Smith, Omar P Sangüeza, Jayson Miedema, Frances A Collichio, Paul B Googe
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Abstract

Melanoma with lymphatic invasion has been associated with increased risk of metastasis, but the mechanisms and clinical implications are poorly understood. Although current reports have documented angiotropic spread of melanoma and suggest lymphatic spread of melanoma to increase the likelihood of metastasis, to our knowledge, lymphangitic metastatic melanoma resembling cutaneous carcinomatosis or presenting with facial hyperpigmentation has not been described. In this case report, we describe extensive cutaneous intralymphatic spread of melanoma, or lymphangitic melanomatosis, producing macular skin pigmentation in a 66-year-old man.
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淋巴管瘤性黑色素瘤病:一名 66 岁男子淋巴内黑色素瘤扩散的病例报告。
有淋巴管侵犯的黑色素瘤与转移风险增加有关,但对其机制和临床影响却知之甚少。尽管目前的报告记录了黑色素瘤的血管扩散,并认为黑色素瘤的淋巴扩散增加了转移的可能性,但据我们所知,淋巴管转移性黑色素瘤类似于皮肤癌转移或表现为面部色素沉着的情况尚未见报道。在本病例报告中,我们描述了一名 66 岁男性的黑色素瘤广泛的皮肤淋巴管内扩散,或淋巴管黑色素瘤病,并在其皮肤上产生黄斑色素沉着。
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