Should Soldiers Take Oral Tranexamic Acid Before Going into Battle?

Nicolas Cazes, Simon-Pierre Corcostegui, Steven Lovi, Emeric Romary, Vincent Desrobert, Lionel Lidzborski, Clément Derkenne
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Abstract

Tranexamic acid is an inexpensive antifibrinolytic treatment that reduces morbidity and mortality in civilian and military trauma patients. It must be administered within 3 hours of the injury, and its efficacy is greater the earlier it is given. It is already used preventively in the civilian environment in a number of indications to reduce bleeding and bleeding-related mortality. We wondered about the potential benefits of preventive oral administration of tranexamic acid prior to an assault for military personnel with a potential risk of injury.
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士兵是否应该在上战场前口服氨甲环酸?
氨甲环酸是一种廉价的抗纤维蛋白溶解治疗药物,可降低平民和军事创伤患者的发病率和死亡率。氨甲环酸必须在受伤后 3 小时内使用,而且越早使用疗效越好。在民用环境中,它已被用于多种适应症的预防性治疗,以减少出血和与出血相关的死亡率。我们想知道,对有潜在受伤风险的军事人员来说,在攻击前预防性口服氨甲环酸有哪些潜在益处。
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