Trauma diagnostic-related target proteins and their detection techniques

IF 4.5 2区 医学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY Expert Reviews in Molecular Medicine Pub Date : 2024-04-11 DOI:10.1017/erm.2024.3
YiLiu Wei, Xiaohan Ren, Zhitao Yuan, Jie Hong, Tao Wang, Weizhi Chen, Yuqing Xu, Jinwang Ding, Jun Lin, Wenqian Jiang, Peng Zhang, Qiaoyi Wu
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Abstract

Trauma is a significant health issue that not only leads to immediate death in many cases but also causes severe complications, such as sepsis, thrombosis, haemorrhage, acute respiratory distress syndrome and traumatic brain injury, among trauma patients. Target protein identification technology is a vital technique in the field of biomedical research, enabling the study of biomolecular interactions, drug discovery and disease treatment. It plays a crucial role in identifying key protein targets associated with specific diseases or biological processes, facilitating further research, drug design and the development of treatment strategies. The application of target protein technology in biomarker detection enables the timely identification of newly emerging infections and complications in trauma patients, facilitating expeditious medical interventions and leading to reduced post-trauma mortality rates and improved patient prognoses. This review provides an overview of the current applications of target protein identification technology in trauma-related complications and provides a brief overview of the current target protein identification technology, with the aim of reducing post-trauma mortality, improving diagnostic efficiency and prognostic outcomes for patients.
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创伤诊断相关靶蛋白及其检测技术
创伤是一个重大的健康问题,它不仅在许多情况下导致直接死亡,而且还会在创伤患者中引起严重的并发症,如败血症、血栓形成、大出血、急性呼吸窘迫综合征和创伤性脑损伤。靶蛋白鉴定技术是生物医学研究领域的一项重要技术,可用于研究生物分子相互作用、药物发现和疾病治疗。它在鉴定与特定疾病或生物过程相关的关键蛋白靶标方面发挥着至关重要的作用,有助于进一步的研究、药物设计和治疗策略的开发。在生物标记物检测中应用靶蛋白技术,可以及时发现创伤患者新出现的感染和并发症,便于迅速采取医疗干预措施,降低创伤后死亡率,改善患者预后。本综述概述了目前靶蛋白鉴定技术在创伤相关并发症中的应用,并简要介绍了目前的靶蛋白鉴定技术,旨在降低创伤后死亡率,提高诊断效率和患者预后效果。
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来源期刊
Expert Reviews in Molecular Medicine
Expert Reviews in Molecular Medicine BIOCHEMISTRY & MOLECULAR BIOLOGY-MEDICINE, RESEARCH & EXPERIMENTAL
CiteScore
7.40
自引率
1.60%
发文量
45
期刊介绍: Expert Reviews in Molecular Medicine is an innovative online journal featuring authoritative and timely Reviews covering gene therapy, immunotherapeutics, drug design, vaccines, genetic testing, pathogenesis, microbiology, genomics, molecular epidemiology and diagnostic techniques. We especially welcome reviews on translational aspects of molecular medicine, particularly those related to the application of new understanding of the molecular basis of disease to experimental medicine and clinical practice.
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