Matthew W. Kaufman, Sarah DeParis, Marily Oppezzo, Cheri Mah, Megan Roche, Levi Frehlich, Michael Fredericson
{"title":"Nutritional Supplements for Healthy Aging: A Critical Analysis Review","authors":"Matthew W. Kaufman, Sarah DeParis, Marily Oppezzo, Cheri Mah, Megan Roche, Levi Frehlich, Michael Fredericson","doi":"10.1177/15598276241244725","DOIUrl":null,"url":null,"abstract":"Background: Healthy aging is defined as survival to advanced age while retaining autonomy in activities of daily living, high societal participation, and good quality of life. Sarcopenia, insomnia, cognitive impairment, and changes in sensation can be key hinderances to healthy aging, but nutritional supplements may abate their impact. As research advances, an updated review on their efficacy on age-related conditions is warranted. Results: Sarcopenia can be mitigated through proper protein intake, supplements like creatine, and in certain situations Branched-Chain Amino Acids and Vitamin D, in adults over 65. Melatonin supplementation has moderate evidence for improving sleep, while valerian root lacks evidence. Magnesium, tart cherry, and kiwifruits have shown promising impacts on sleep in limited articles. Magnesium, Vitamin D, and B vitamin supplementation have been shown to improve cognition in those with mild cognitive impairment and Alzheimer’s disease but require further study prior to recommendation. The Age-Related Eye Disease Study supplement combination is routinely recommended to reduce risk of progression to advance stages of age-related macular degeneration. Alpha-Lipoic Acid and Folate have been investigated for their roles in mitigating age-related hearing losses. Conclusions: Nutritional supplements and lifestyle changes may mitigate disabilities across multiple domains of age-related illnesses and promote healthy aging.","PeriodicalId":47480,"journal":{"name":"American Journal of Lifestyle Medicine","volume":null,"pages":null},"PeriodicalIF":1.5000,"publicationDate":"2024-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"American Journal of Lifestyle Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1177/15598276241244725","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Healthy aging is defined as survival to advanced age while retaining autonomy in activities of daily living, high societal participation, and good quality of life. Sarcopenia, insomnia, cognitive impairment, and changes in sensation can be key hinderances to healthy aging, but nutritional supplements may abate their impact. As research advances, an updated review on their efficacy on age-related conditions is warranted. Results: Sarcopenia can be mitigated through proper protein intake, supplements like creatine, and in certain situations Branched-Chain Amino Acids and Vitamin D, in adults over 65. Melatonin supplementation has moderate evidence for improving sleep, while valerian root lacks evidence. Magnesium, tart cherry, and kiwifruits have shown promising impacts on sleep in limited articles. Magnesium, Vitamin D, and B vitamin supplementation have been shown to improve cognition in those with mild cognitive impairment and Alzheimer’s disease but require further study prior to recommendation. The Age-Related Eye Disease Study supplement combination is routinely recommended to reduce risk of progression to advance stages of age-related macular degeneration. Alpha-Lipoic Acid and Folate have been investigated for their roles in mitigating age-related hearing losses. Conclusions: Nutritional supplements and lifestyle changes may mitigate disabilities across multiple domains of age-related illnesses and promote healthy aging.
背景:健康老龄化的定义是,在保持日常生活自理能力、较高的社会参与度和良好的生活质量的同时,还能存活到晚年。肌肉疏松症、失眠、认知障碍和感觉变化可能是阻碍健康老龄化的主要因素,但营养补充剂可以减轻它们的影响。随着研究的不断深入,有必要对营养补充剂对老年相关疾病的疗效进行最新评述。结果:对于 65 岁以上的成年人来说,通过摄入适当的蛋白质、肌酸等营养补充剂,以及在某些情况下补充支链氨基酸和维生素 D,可以缓解 "肌肉疏松症"。褪黑素补充剂在改善睡眠方面有中等程度的证据,而缬草根则缺乏证据。在有限的文章中,镁、酸樱桃和猕猴桃对睡眠有良好的影响。镁、维生素 D 和 B 族维生素补充剂已被证明可改善轻度认知障碍和阿尔茨海默氏症患者的认知能力,但在推荐之前还需要进一步研究。老年性眼病研究》常规推荐补充剂组合,以降低老年性黄斑变性发展到晚期的风险。阿尔法硫辛酸和叶酸在减轻老年性听力损失方面的作用已得到研究。结论营养补充剂和生活方式的改变可减轻多种老年相关疾病的残疾,促进健康老龄化。