Thomas Uslar, Roberto Olmos, Alberth Burnier, Benjamín Sanfuentes, Pauline Böhm, Maria Paz Orellana, Francisco J. Guarda, Álvaro Huete, Nicolás Mertens, Cecilia Besa, Marcelo Andía, Alejandro Majerson, Jaime Cartes, Carlos Fardella, Fidel Allende, Sandra Solari, Anand Vaidya, Rene Baudrand
{"title":"The Spectrum from Overt Primary Aldosteronism to Mild Dysregulated Aldosterone Production in Incidentally Discovered Adrenocortical Adenomas","authors":"Thomas Uslar, Roberto Olmos, Alberth Burnier, Benjamín Sanfuentes, Pauline Böhm, Maria Paz Orellana, Francisco J. Guarda, Álvaro Huete, Nicolás Mertens, Cecilia Besa, Marcelo Andía, Alejandro Majerson, Jaime Cartes, Carlos Fardella, Fidel Allende, Sandra Solari, Anand Vaidya, Rene Baudrand","doi":"10.1101/2024.04.10.24305640","DOIUrl":null,"url":null,"abstract":"<strong>Background</strong> Incidental adrenocortical adenomas (IA) are common. Current guidelines suggest screening for primary aldosteronism (PA) only in cases of hypertension or hypokalemia. This study aimed to evaluate the spectrum from overt PA to mild dysregulated aldosterone production with a sensitive protocol irrespective of blood pressure (BP) and potassium in patients with IA.","PeriodicalId":501419,"journal":{"name":"medRxiv - Endocrinology","volume":"42 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"medRxiv - Endocrinology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1101/2024.04.10.24305640","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract
Background Incidental adrenocortical adenomas (IA) are common. Current guidelines suggest screening for primary aldosteronism (PA) only in cases of hypertension or hypokalemia. This study aimed to evaluate the spectrum from overt PA to mild dysregulated aldosterone production with a sensitive protocol irrespective of blood pressure (BP) and potassium in patients with IA.
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